Cytogenetic Laboratory Management

Author: Susan Mahler Zneimer
Publisher: John Wiley & Sons
ISBN: 9781119069775
Release Date: 2017-01-27
Genre: Science

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for laboratory developed tests, and pre-clinical validation study designs. The second focus of the book describes best practices for staffing and training, including cost of testing, staffing requirements, process improvement using Six Sigma techniques, training and competency guidelines and complete training programs for cytogenetic and molecular genetic technologists. The third part of the text provides step-wise standard operating procedures for chromosomal, FISH and microarray-based tests, including pre-analytic, analytic and post-analytic steps in testing, and divided into categories by specimen type, and test-type. All three sections of the book include example worksheets, procedures, and other illustrative examples that can be downloaded from the Wiley website to be used directly without having to develop prototypes in your laboratory. Providing both a wealth of information on laboratory management and molecular and cytogenetic testing, Cytogenetic Laboratory Management will be an essential tool for laboratorians world-wide in the field of laboratory testing and genetics testing in particular. This book gives the essentials of: Developing and implementing good quality management programs in laboratories Understanding design control of tests and pre-clinical validations studies and reports FDA guidelines for laboratory developed tests Use of reagents, instruments and equipment Cost of testing assessment and process improvement using Six Sigma methodology Staffing training and competency objectives Complete training programs for molecular and cytogenetic technologists Standard operating procedures for all components of chromosomal analysis, FISH and microarray testing of different specimen types This volume is a companion to Cytogenetic Abnormalities: Chromosomal, FISH and Microarray-Based Clinical Reporting. The combined volumes give an expansive approach to performing, reporting and interpreting cytogenetic laboratory testing and the necessary management practices, staff and testing requirements.

Cytogenetic Abnormalities

Author: S. Zneimer
Publisher: John Wiley & Sons
ISBN: 9781118412565
Release Date: 2014-08-21
Genre: Science

This guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports. Part one of the guide explores chromosomal, FISH, and microarray analysis in constitutional cytogenetic analyses, while part two looks at acquired abnormalities in cancers. Both sections provide illustrative examples of chromosomal abnormalities and how to communicate these findings in standardized laboratory reports.

The AGT Cytogenetics Laboratory Manual

Author: Marilyn S. Arsham
Publisher: John Wiley & Sons
ISBN: 9781119061229
Release Date: 2017-04-24
Genre: Science

Cytogenetics is a segment of the evolving cytogenomic branch of genetics that explores the genetic makeup of a cell, in particular chromosomes both in metaphase and in interphase cycles, as well as at the molecular level. It utilizes an assortment of procedures to illuminate both the full complement of chromosomes and a targeted region within a specific chromosome. These investigative tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive treatment of the diagnostic tests offered by this clinical laboratory environment and explains the scientific theories behind those procedures. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters that reflect the intuitive experience of its authors. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN's cytogenetic language; tips for laboratory management; examples of laboratory information systems; a collection of Internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student with a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the multiple facets behind each of these procedures. Topic coverage is rich in detail, yet presented with the student in mind, making it a useful resource for researchers, clinicians, and laboratory professionals, as well as students in a university or medical school that offers introductory or laboratory-related courses exploring cytogenetics' role within medical genetics. Reviews for the third edition: "A collection of protocols and explanations for cytogenetic techniques from the common to the peculiar." "An excellent book. Looking forward to an updated version."

The Principles of Clinical Cytogenetics

Author: Steven L. Gersen
Publisher: Springer Science & Business Media
ISBN: 9781441916884
Release Date: 2013-03-26
Genre: Medical

In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full chapter devoted to advances in chromosome microarray, soon to become a standard of care in this field, as well as an update on chromosome nomenclature as reflected in ISCN 2009. Other features include an update on automation to reflect the current state of the art, an update on hematopoietic neoplasms to reflect the new WHO guidelines, and updates on all regulatory changes that have been implemented. Cutting edge and readily accessible, The Principles of Clinical Cytogenetics, Third Edition offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, graduate and medical students studying for board examinations, cytogenetics technologists, and cytogeneticists a clear understanding of what happens in the cytogenetics laboratory to facilitate accurate and timely diagnoses.

Advanced Building Technologies for Sustainability

Author: Asif Syed
Publisher: John Wiley & Sons
ISBN: 9780470546031
Release Date: 2012-07-03
Genre: Architecture

Practical solutions for sustainability In this timely guide, one of the world's leaders in advanced building technology implementation shows architects and engineers proven and practical methods for implementing these technologies in sustainably-designed buildings. Because of the very limited time architects are given from being awarded a project to concept design, this book offers clear and workable solutions for implementing solar energy, radiant heating and cooling floors, displacement ventilation, net zero, and more. It provides helpful tips and suggestions for architects and engineers to work together on implementing these technologies, along with many innovative possibilities for developing a truly integrated design. This book also explores and explains the many benefits of advanced technologies, including reduced greenhouse gas emissions, lower operating costs, noise reduction, improved indoor air quality, and more. In addition, Advanced Building Technologies for Sustainability: Offers detailed coverage of solar energy systems, thermal energy storage, geothermal systems, high-performance envelopes, chilled beams, under-floor air distribution, displacement induction units, and much more Provides case studies of projects using advanced technologies and demonstrates their implementation in a variety of contexts and building types Covers the implementation of advanced technologies in office towers, large residential buildings, hospitals, schools, dormitories, theaters, colleges, and more Complete with a clear and insightful explanation of the requirements for and benefits of acquiring the U.S. Green Building Council's LEED certification, Advanced Building Technologies for Sustainability is an important resource for architects, engineers, developers, and contractors involved in sustainable projects using advanced technologies.

Field Experience

Author: Naijian Zhang
Publisher: SAGE Publications
ISBN: 9781483383415
Release Date: 2015-02-11
Genre: Social Science

A blueprint for doing clinical work in field experience, Field Experience: Transitioning from Student to Professional aids students in developing their professional identity on their journey toward becoming a counselor. Authors Naijian Zhang and Richard D. Parsons help students integrate the knowledge they learn across the curriculum by presenting a roadmap of how to start, navigate, and finish a practicum or internship. Throughout the book, coverage of CACREP standards, case illustrations, exercises, and real-life examples create an accessible overview of the entire transitioning process. Field Experience is part of the SAGE Counseling and Professional Identity Series, which targets specific competencies identified by CACREP (Council for Accreditation of Counseling and Related Programs).

Hands On Mobile App Testing

Author: Daniel Knott
Publisher: Addison-Wesley Professional
ISBN: 9780134191799
Release Date: 2015-05-08
Genre: Computers

The First Complete Guide to Mobile App Testing and Quality Assurance: Start-to-Finish Testing Solutions for Both Android and iOS Today, mobile apps must meet rigorous standards of reliability, usability, security, and performance. However, many mobile developers have limited testing experience, and mobile platforms raise new challenges even for long-time testers. Now, Hands-On Mobile App Testing provides the solution: an end-to-end blueprint for thoroughly testing any iOS or Android mobile app. Reflecting his extensive real-life experience, Daniel Knott offers practical guidance on everything from mobile test planning to automation. He provides expert insights on mobile-centric issues, such as testing sensor inputs, battery usage, and hybrid apps, as well as advice on coping with device and platform fragmentation, and more. If you want top-quality apps as much as your users do, this guide will help you deliver them. You’ll find it invaluable–whether you’re part of a large development team or you are the team. Learn how to Establish your optimal mobile test and launch strategy Create tests that reflect your customers, data networks, devices, and business models Choose and implement the best Android and iOS testing tools Automate testing while ensuring comprehensive coverage Master both functional and nonfunctional approaches to testing Address mobile’s rapid release cycles Test on emulators, simulators, and actual devices Test native, hybrid, and Web mobile apps Gain value from crowd and cloud testing (and understand their limitations) Test database access and local storage Drive value from testing throughout your app lifecycle Start testing wearables, connected homes/cars, and Internet of Things devices

The Google Model

Author: Annika Steiber
Publisher: Springer Science & Business Media
ISBN: 9783319042084
Release Date: 2014-04-14
Genre: Business & Economics

This book shows how companies like Google have reinvented the common practice in management in order to continuously innovate in fast changing industries. With the ever-increasing pace of change, reinventing existing management principles could become a necessity and prove crucial in the long-term competitiveness of many companies. The book presents a unique synthesis of findings from leading research on long-term competitiveness in fast changing industries. The core of the study comprises an exclusive 1-year in-depth research study on the drivers of innovation at Google and includes examples on how Google has translated the reinvented management principles into practice. The book also offers key action-points to help practitioners in reinventing their own management models for continuous innovation.

Building the Future

Author: Amy Edmondson
Publisher: Berrett-Koehler Publishers
ISBN: 9781626564206
Release Date: 2016-04-18
Genre: Business & Economics

Building the Future Machiavelli famously wrote, “There is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success than to take the lead in the introduction of a new order of things.” That's what this book is about—innovation far more audacious than a new way to find a restaurant or a smart phone you can wear on your wrist. Amy C. Edmondson and Susan Salter Reynolds explore large-scale systemic innovation that calls for “big teaming”: intense collaboration between professions and industries with completely different mindsets. This demands leadership combining an expansive vision with deliberative incremental action—not an easy balance. To explore the kind of leadership required to build the future we need, Edmondson and Reynolds tell the story of Living PlanIT. This award-winning “smart city” start-up was launched with a breathtakingly ambitious goal: creating a showcase high-tech city from scratch to pilot its software—quite literally setting out to build the future. This meant a joint effort spanning a truly disparate group of software entrepreneurs, real estate developers, city government officials, architects, construction companies, and technology corporations. By taking a close look at the work, norms, and values in each of these professional domains, we gain new insight into why teaming across fields is so challenging. And we get to know Living PlanIT's leaders, following them and their partners through cycles of hope, exhaustion, disillusionment, pragmatism, and renewal. There are powerful lessons here for anyone, in any industry, seeking to drive audacious innovation.

Geometric Design of Roads Handbook

Author: Keith M. Wolhuter
Publisher: CRC Press
ISBN: 9781482288728
Release Date: 1994-12-08
Genre: Technology & Engineering

Explore the Art and Science of Geometric Design The Geometric Design of Roads Handbook covers the design of the visible elements of the road—its horizontal and vertical alignments, the cross-section, intersections, and interchanges. Good practice allows the smooth and safe flow of traffic as well as easy maintenance. Geometric design is covered in depth. The book also addresses the underpinning disciplines of statistics, traffic flow theory, economic and utility analysis, systems analysis, hydraulics and drainage, capacity analysis, coordinate calculation, environmental issues, and public transport. Background Material for the Practicing Designer A key principle is recognizing what the driver wishes to do rather than what the vehicle can do. The book takes a human factors approach to design, drawing on the concept of the "self-explaining road." It also emphasizes the need for consistency of design and shows how this can be quantified, and sets out the issues of the design domain context, the extended design domain concept, and the design exception. The book is not simply an engineering manual, but properly explores context-sensitive design. Discover and Develop Real-World Solutions Changes in geometric design over the last few years have been dramatic and far-reaching and this is the first book to draw these together into a practical guide which presents a proper and overriding philosophy of design for road and highway designers, and students. This text: Covers the basics of geometric design Explores key aspects of multimodal design Addresses drainage and environmental issues Reviews practical standards, procedures, and guidelines Provides additional references for further reading A practical guide for graduate students taking geometric design, traffic operations/capacity analysis, and public transport, the Geometric Design of Roads Handbook introduces a novel approach that addresses the human aspect in the design process and incorporates relevant concepts that can help readers create and implement safe and efficient designs.

Chasing the Heiress

Author: Rachael Miles
Publisher: Zebra Shout
ISBN: 9781420140897
Release Date: 2016-05-31
Genre: Fiction

“Intrigue, romance, adventure—Chasing the Heiress has it all. I’m a Rachel Miles fan!”—Cathy Maxwell, New York Times bestselling author "Her characters come alive with warmth and purpose." --Jodi Thomas, New York Times bestselling author Heiress On The Run Lady Arabella Lucia Fairborne has no need of a husband. She has a fine inheritance for the taking, a perfectly capable mind, and a resolve as tough as nails. But what she doesn't have is the freedom to defy her cousin's will--and his will is to see her married immediately to the husband of his choosing. So is it any wonder that she dresses herself as a scullery maid and bolts into the night? Colin Somerville's current mission for the home office is going poorly. Who would have expected otherwise for a rakish spy tasked with transporting a baby to the care of the royal palace. But when, injured and out of ideas, Colin stumbles upon a beautiful maid who knows her way around a sickroom, it seems salvation has arrived. Until he realizes that though Lucy may be able to help him survive his expedition, he may not escape this ordeal with his heart intact…

Library Technology and Digital Resources

Author: Marie Keen Shaw
Publisher: Rowman & Littlefield
ISBN: 9781442256453
Release Date: 2015-11-12
Genre: Language Arts & Disciplines

In the last decade library collections have rapidly evolved from a predominance of print books and journals to an ever growing mix of digital and print resources. Library patrons are predominately served by support staff that is expected to know how to help patrons select and use digital resources. Yet most library support staff (LSS) has not had training to become proficient in finding, using, and instructing others in the abundance of the digital resources of websites, databases, e-texts, digital libraries and their related technologies. Library Technology and Digital Resources: An Introduction for Support Staff is both a text for professors who teach in library support staff programs and an introductory reference manual for support staff who work in libraries. This book will guide the LSS to be able to: Distinguish key features and enhancements found among vendors and providers of digital libraries, digital collections, databases, and e-texts; Plan, budget, fund and write grants for digital resources; Understand the complexity and options of licensing and usage agreements for digital resources; Know copyright permissions and acceptable use guidelines for digital resources. Understand the basic technologies that support library digital resources including network structures, software applications, and protocols; Distinguish between directories and search engines as they relate to digital resources as well as be able to employ advance search skills effectively; Explore the resources of global, national, and state digital libraries and their collections; Use government databases and other digitized systems and information sources; Find exemplary digital resources though other agencies such as museums, university collections and other sources that librarians can share with patrons. Create local digital resources of primary and historical materials and artifacts with metadata and cataloging for searchable access. Interpret meaning from library digital resources using visual literacy skills. Promote library digital resources through a variety of means including social media and online options.

Stellar Customer Service Training Library Staff to Exceed Expectations

Author: Mou Chakraborty
Publisher: ABC-CLIO
ISBN: 9781440840777
Release Date: 2016-08-29
Genre: Language Arts & Disciplines

From librarians to volunteer workers, staff to student workers, all library personnel need to deliver great customer service. This book presents innovative instructional methods that will inspire you to take a fresh approach to customer service training. • Provides model staff training programs that have been proven successful in real-world applications • Addresses how to improve the delivery of customer service at all levels of personnel—librarians, general staff, student workers, and volunteers • Includes guidelines on re-training and evaluation of customer service training needs

Measurement and Evaluation in Human Performance

Author: James R. Morrow
Publisher: Human Kinetics 1
ISBN: 0736065032
Release Date: 2006-06-01
Genre: Education

Measurement and Evaluation in Human Performance, Third Edition,offers unmatched, in-depth instruction in measurement and evaluation techniques. Thoroughly revised and updated, the third edition features a new section on epidemiology and further develops international perspectives. This edition also features improved readability in measurement statistics and enhanced efficiency in solving measurement and evaluation problems through the use of the Statistical Package for the Social Sciences (SPSS). Additional features that are new to this edition: -Revised first chapter that lays the groundwork for improved learning throughout the text -Inclusion of a specific downloadable data set that is used as an example in many chapters -Removal of outdated and complicated statistical techniques, eliminating the need for a background in higher-level mathematics -Additional computer tasks in each chapter that tie earlier learning to specific applications -Decision scenarios similar to those made by human performance professionals to help students apply decision making skills to practical, real-life problems The text also increases the number of problem sets and places a greater emphasis on student-friendly learning through its learning aids, including chapter objectives, measurement and evaluation challenges, highlight features, mastery items, and new computer tasks for each chapter. Measurement and Evaluation in Human Performance, Third Edition,will appeal to students by engaging them in the material to increase their comprehension, and to professionals through its depth of information and ease in locating it. Includes an online study guide! To assist students using the text, Measurement and Evaluation in Human Performance, Third Edition, has a companion online student study guide that allows students to interactively practice, review, and develop their understanding of measurement and evaluation processes so that they can make strong grades and valid decisions. Students will receive free access to the study guide with the purchase of a new text, or it may be purchased as a separate component The online study guide is designed to help students learn, understand, and practice the main concepts of each chapter. Students will find selected answers to mastery items from the text, homework problems, selected homework answers, data matrixes to download, and multiple choice quizzes designed to test their knowledge of the textbook material. They will also find lecture outlines created by the authors to help them learn the key concepts, as well as links to related sites on the Web and a variety of test tips.