Author: Iris Schrijver
Publisher: Springer Science & Business Media
Release Date: 2011-09-09
This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.
Author: Debra G.B. Leonard
Release Date: 2016-02-02
This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.
Dieses interdisziplinäre Nachschlagewerk bietet Ihnen das Fundament für Ihre exakte Diagnose und gezielte Therapie-Planung. o Sie erhalten einen praxisorientierten Überblick über alle modernen und etablierten Diagnostik-Verfahren. o Didaktisch übersichtlich stehen die jeweiligen radiologischen und pathologisch-anatomischen Strukturen dem Text gegenüber. o Kurzgefaßte Therapievorschläge ergänzen die diagnostischen Richtlinien. => Das aktuelle Nachschlagewerk für die multidisziplinäre Zusammenarbeit von Orthopäden, Radiologen, Rheumatologen und Pathologen. Schnell * präzise * praxisgerecht
Author: Raymond R. Tubbs
Publisher: Elsevier Health Sciences
Release Date: 2008-09-22
This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
Author: Klaus Gottlieb
Publisher: Springer Science & Business Media
Release Date: 2013-10-12
The available textbooks on endoscopic ultrasound (EUS) typically focus on technique and interpretation of commonly observed images and scenarios and are aimed primarily at trainees. However, independent practitioners of EUS are often challenged by unusual cases which they are expected to handle competently despite the absence of authoritative guidance. The Diagnostic Endosonography aims to fill this gap by presenting carefully selected cases that will expand the practitioner’s knowledge base and cover important clinical challenges. The case material is organized principally according to anatomic site. Approximately 170 case reports are included, each of which is accompanied by an average of three to five high-quality EUS images; in addition, CT and PET scans are shown when appropriate. For each case, the case description is followed by helpful “teaching points” as well as up-to-date literature references and suggestions for future research.
Author: Howard Reisner
Publisher: McGraw Hill Professional
Release Date: 2014-09-22
A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.
Author: William B. Coleman
Publisher: Academic Press
Release Date: 2016-10-05
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests
Author: Richard A. McPherson
Publisher: Elsevier Health Sciences
Release Date: 2011-09-06
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.
Ist die Psyche nichts als die neuronalen Prozesse im Gehirn? Müssen zentrale mentale Begriffe wie Selbst, Bewusstsein, Unbewusstsein, etc. durch neuronale Mechanismen erklärt werden und die Psychiatrie durch die Neurowissenschaften ersetzt werden? Unser Buch zeigt auf, dass mentale Prozesse und psychische Symptome bei psychiatrischen Erkrankungen wie Schizophrenie, Depression, etc. weder reine geistige noch nur neuronale Prozesse sind. Gehirn ist immer auch schon Umwelt; und es ist die Interaktion der Umwelt-Gehirn-Beziehung, in der psychische Phänomene inklusive ihrer Abnormitäten ihren neuropsychodynamischen Ursprung haben. Der Inhalt Neuropsychodynamische Grundlagen Neurosoziale Auffassung des Gehirns Psychoanalytische Konzepte und deren Weiterentwicklung Neuropsychodynamik psychischer Störungen Therapie auf neuropsychodynamischer Grundlage Neurosoziale und neuropsychodynamische Zukunftsperspektiven Die Herausgeber Prof. Dr. Heinz Böker, Psychiatrische Universitätsklinik Zürich, Zentrum für Depressionen, Angsterkrankungen und Psychotherapie, Zürich, Schweiz. Prof. Dr. Peter Hartwich, Städtische Kliniken Frankfurt am Main-Höchst, Klinik für Psychiatrie und Psychotherapie/Psychosomatik, Akademisches, Lehrkrankenhaus der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Deutschland. Prof. Dr. Dr. Georg Northoff, University of Ottawa, Institute of Mental Health Research, Royal Ottawa Mental Health Centre, Ottawa/ON, Canada, Zhejang University, Hangzhou/China, Taipeh Medical University Taipeh/Taiwan.
Author: Mai P. Hoang
Release Date: 2014-06-26
Melanocytic Lesions: A Case Based Approach provides a concise yet comprehensive guideline on how to diagnose common as well as problematic and challenging melanocytic lesions. In the first 11 chapters, each entity is illustrated by an actual case; followed by discussion of how the diagnosis is reached, of the histologic differential diagnoses and of diagnostic pitfalls and ends with bulleted teaching points. Pertinent and up to date references are included at the end of each chapter. The latter chapters cover current microstaging and classification of melanoma, ancillary techniques including immunohistochemistry as well as available molecular assays and molecular targeted therapy. All figures and glass slides of the discussed cases are hosted online for easy viewing and access. Melanocytic Lesions: A Case Based Approach will serves as a useful resource for pathologists, dermatologists and researchers dealing with melanocytic lesions.