Author: Sarah Wolfensohn
Publisher: John Wiley & Sons
Release Date: 2013-01-03
This bestseller has been an essential book for all those working with laboratory animals since it was first published in 1994. This fourth edition retains all the classic features that have made it a must-have reference including emphasis on best practice in order to improve animal welfare. The contents have been thoroughly updated and reorganised to make sure it is a really practical book for day-to-day use in the laboratory. The first section of the book covers principles applicable to all species, for example husbandry, handling and the education and training required by scientists and technical staff working with animals in the laboratory. Later chapters focus on specific species or groups of species. New to this edition: • Reflects changes in European legislation and their impact on national legislation • Covers recommendations for the education and training of those carrying out animal experiments across Europe • New chapters on ethical considerations and balancing animal welfare with science • New information on environmental enrichment for laboratory animals • Covers advancements in anaesthesia and analgesia and techniques • Spiral bound for ease-of-use as a bench-top reference This book is ideal for all personnel carrying out scientific procedures using animals, particularly during training and also for the new researcher. It will also be essential reading for study directors designing research programmes, animal technicians and veterinarians working with laboratory animal species.
Author: Robert C. Hubrecht
Publisher: John Wiley & Sons
Release Date: 2010-01-19
The seminal reference on the care of laboratory and captive animals, The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals is a must-have for anyone working in this field. The UFAW Handbook has been the definitive text since 1947. Written for an international audience, it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providing comprehensive coverage, with all chapters being peer reviewed by anonymous referees. As well as addressing the husbandry of laboratory animals, the content is also of great value to zoos and aquaria. Changes for the eighth edition: Revised and updated to reflect developments since publication of the previous edition. New chapters on areas of growing concern, including: the 3Rs; phenotyping; statistics and experimental design; welfare assessment; legislation; training of people caring for lab animals; and euthanasia. All material combined into one volume for ease of reference. This book is published on behalf of UFAW (The Universities Federation for Animal Welfare), with whom we also publish the UFAW/Wiley-Blackwell Animal Welfare Book Series. This major series of books provides an authoritative source of information on worldwide developments, current thinking and best practice in the field of animal welfare science and technology. For details of all of the titles in the series see www.wiley.com/go/ufaw.
Rodents are the most commonly used species in biomedical research. Individuals conducting rodent research are often responsible to ensure that all areas of anesthesia and analgesia are performed humanely. Anesthetic agent selection, anesthetic monitoring, and postoperative pain assessment and management are essential to the institutional animal care and use program and contribute significantly to the 3Rs by reducing pain and/or distress and refining various procedures. The Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents is the first book to capture multiple advances in this important area that greatly impacts various experimental methodologies. Richly illustrated in full color, the book serves as a quick reference source for investigators, veterinarians, technicians, and other animal caretakers charged with the care and use of rodents in a research setting. The unique format of this book also makes it extremely valuable to IACUC members, institutional officials, and occupational health and safety professionals.
Author: Jann Hau
Publisher: CRC Press
Release Date: 2010-12-02
Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences and all rely on access to high-quality laboratory animals as models for humans. Rooted in the principle that good science can only be performed in environments that promote good animal welfare, this third edition of the bestselling Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices emphasizes the importance of implementing the three R’s: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort, and integrates these humane principles into almost every chapter. See what's new in the Third Edition: New chapters: Applications of Radio-Telemetry in Small Laboratory Animals, Generation and analysis of genetically modified mice, and Physiological, Hematological, and Clinical Chemistry Parameters Additional mateiral on the international harmonization of practices and on the continued implementation of the refinement, reduction, and replacement of animal usage in laboratories Sixteen page color insert Relevant to virtually all areas of laboratory science and forming the cornerstone of laboratory animal science, each individual chapter focuses on an important subdiscipline of laboratory animal science including humane laws and guidelines; non-surgical, surgical, microsurgical, and post-mortem procedures; genetic modification; nutrition, feeding, and environmental factors; experiment design and alternative methods; and analgesia, anesthesia, and euthanasia. Each chapter can be read in series or as a stand alone text. A truly international effort from world renowned contributors, Handbook of Laboratory Animal Science, Vol. 1, Essential Principles and Practices, Third Edition is useful as a textbook in laboratory animal science courses for postgraduate and undergraduate students, as a handbook for scientists who work with animals in their research, and for university veterinarians, regulators, and other specialists in laboratory animal science.
Author: Y. B. Rajeshwari
Publisher: New India Publishing
Release Date: 2009-06-09
It is now an established fact that laboratory animals play a very vital role in bio-chemical research particularly in the drug development programmes. The book Includes comprehensive and updated information on all the topics, which is presented in a precise manner in a simple language, which becomes easy for students to understand. Further, with the touch of personal communication of authors out of their enriched experience in profession, for considerable long time, the information becomes more educative and lucrative for students as well as for the teacheThe book contains information on pet animals and animal welfare and ethics.
Mit diesem Buch liegt nunmehr die deutsche Fassung des weltweit geschAtzten Lehrbuches zur Physiologie der Tiere von Knut Schmidt-Nielsen vor. Die prAgnante Darstellung von Fakten und der klare Stil sind sein Markenzeichen. Was zeichnet ein gut lesbares Lehrbuch aus, mit dem man sich exzellent auf PrA1/4fungen vorbereiten kann? Nicht die FA1/4lle an Fakten, sondern eine klare und gut verstAndliche Darstellung sowie die MAglichkeit, sich ZusammenhAnge selbst zu erschlieAen und so in dieses Wissensnetz Fakten einzubauen. Diesen Anspruch vermag Schmidt-Nielsen in seinem bereits in der 5. englischen Auflage vorliegenden Lehrbuch auf exzellente Weise zu erfA1/4llen. Der Schwerpunkt des Buches liegt auf den Grundprinzipien der Funktion von Organen und Geweben. Das Wissen der Physiologie erschlieAt sich somit A1/4ber die ZusammenhAnge mit den Akologischen Parametern Sauerstoff, Nahrung und Energie, Temperatur und Wasser -- und das aus einer Hand. Knut Schmidt-Nielsen ist emeritierter Professor fA1/4r Tierphysiologie an der Duke University in Durham. Er ist Mitglied der National Academy of Sciences und erhielt 1992 den International Prize for Biology, das japanische A"quivalent des Nobel-Preises. Titelbild: Die colorierte rasterelektronenmikroskopische Aufnahme zeigt Schuppen eines Silberfischchens. (A(c)) eye of scinece/Oliver Meckes hysiologie werden aus diesem Buch eine Menge lernen und e
Author: Frank G.J. Hayhoe
Release Date: 2013-03-08
Dieses Buch wird als Atlas bezeichnet, nicht als Lehrbuch. Wir nehmen an, daß sein Benutzer Zugang zum Inhalt der Standardwerke theoretischer und praktischer Hämatologie hat. Wir haben daher nicht die Absicht, deren Dar legungen zu wiederholen. Wir sind der festen Uberzeugung, daß es keinen Ersatz für eigene Bemühungen um mikroskopische Präparate gibt. um Ver ständnis für die hämatologische Zytologie zu gewinnen, aber wir sind ebenfalls überzeugt, daß eine Sammlung von Farbmikrophotos eine nutzliche Ergänzung solcher mikroskopischer Studien darstellen kann. Es existieren gute Atlanten der Hämatologie, aber es besteht Bedarf für einen nicht zu umfangreichen Band von ausgezeichneten Mikrophotos üblicher Große, die eine praktische Hilfe für den täglichen Gebrauch am Mikroskopiertisch sind. Dies zu erreichen war unsere Absicht. Die Abbildungen zeigen Beispiele der meisten Zelltypen, auf die man üblicherweise stoßt. und einige, die seltener sind, aber wir haben eine ein seitige Darstellung von Seltenheiten vermieden. Wir haben auch keine Auswahl von überscharfen photogenen Ausschnitten getroffen, da unser Objektiv eher der Wirklichkeit als der Perfektion folgte. Wir beurteilen die Verschiedenheit in Färbung und Hintergrund unter der Sammlung von Aufnahmen nicht als praxis feindlich, sondern als Hilfe beim Abschätzen der farberischen Variationen, die bei den meisten Färbemethoden im Liblichen Laboratorium eingeschlossen sind.
Author: Jann Hau
Publisher: CRC Press
Release Date: 2013-12-26
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs—replace, reduce, refine—which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines. The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models. This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.
Author: Axel Kornerup Hansen
Publisher: CRC Press
Release Date: 2014-11-11
The Handbook of Laboratory Animal Bacteriology, Second Edition provides comprehensive information on all bacterial phylae found in laboratory rodents and rabbits to assist managers, veterinary pathologists and laboratory animal veterinarians in the management of these organisms. The book starts by examining the general aspects of bacteriology and how to sample and identify bacteria in animals. It then describes the most relevant species within each phylum and discusses the impact they may have on research. Emphasizing those bacteria known to interfere with research protocols, the book offers methods for isolation and differentiation among related bacteria. It discusses where to purchase reagents for rodent bacteriology and outlines standards for safety in a bacteriological laboratory. Highlights of the second edition: Focuses on modern sequencing techniques based on molecular identification Reorganizes content according to modern systematics based on new identification methods Presents new chapters on mechanisms behind bacterial impact on animal models and on the systematic classification of bacteria Provides information on a range of bacteria interfering with animal models for human disease, not only for those bacteria which cause disease in laboratory animal colonies Includes new figures in color and with enhanced resolution The book is essential reading for those interested in the management of organisms known to interfere with the colony health of rabbits and rodents used in research protocols—including facility managers, clinical veterinarians, veterinary pathologists, and researchers.
Author: John Webster
Publisher: John Wiley & Sons
Release Date: 2011-04-18
Through successive editions, Management and Welfare of Farm Animals has gained international recognition as a classic introductory textbook for students of agriculture and veterinary science. Conceived by the Universities Federation for Animal Welfare (UFAW), the book has always sought to promote the humane treatment of livestock within the practical business context of modern farming. Now fully revised and updated, this fifth edition remains the most comprehensive and accessible guide available. Three animal groups appear here for the first time (game birds, South American camelids, and ostriches), and a chapter on horses has also been restored. Throughout, the book offers clear advice for the humane management of all major farmed species in the primary context of large-scale food production. However, this edition also takes full account of consumer demand (and legal requirements) for alternative farming methods and enhanced welfare standards, whether in conventional agriculture or the smallest of 'hobby' farms. Brand new chapters reflect fresh understanding of welfare science, ethics, and the role of society in ensuring the best possible farm conditions. It remains an indispensable resource for students, and for all those seeking to promote animal welfare. Published as a part of the prestigious Wiley-Blackwell – UFAW Animal Welfare series. UFAW, founded 1926, is an internationally recognised, independent, scientific and educational animal welfare charity. For full details of all titles available in the UFAW series, please visit www.wiley.com/go/ufaw.
Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution’s IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee. This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare’s Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.