Author: Steen Honor? Hansen
Publisher: John Wiley & Sons
Release Date: 2011-12-12
This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples
Author: A. H. Beckett
Publisher: A&C Black
Release Date: 1988
This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.
Author: Donald Cairns
Publisher: Pharmaceutical Press
Release Date: 2012-01-01
An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems. The 4th edition includes new chapters on Chromatographic Methods of Analysis, and Medicinal Chemistry - The Science of Drug Design.
Author: Douglas A. Skoog
Release Date: 2013-04-17
Mit der deutschsprachigen Ausgabe des Standard-Lehrbuchs zur Instrumentellen Analytik von Skoog und Leary schließt sich endlich eine Lücke im Buchangebot für fortgeschrittene Studenten der Chemie an Universitäten und Fachhochschulen. Aufgrund des multidisziplinären Eindringens der Analytischen Chemie in andere Bereiche richtet sich das Buch auch an Physiker, Ingenieure und Biochemiker. Das Buch führt aktuell und kompetent in die Grundzüge und Feinheiten der heutigen Instrumentellen Analytischen Chemie ein. Über 530 detailreiche, selbsterklärende Abbildungen, Anhänge zu Statistik und Elektronik, Übungsaufgaben mit Lösungen und viele wichtige Originalzitate ergänzen dieses moderne Lehrbuch für Studierende und Praktiker.
Author: Heather Hattori
Publisher: John Wiley & Sons
Release Date: 2016-02-02
Etwas lernen ist eine Sache, es später umzusetzen noch einmal eine ganz andere. Aber keine Sorge, dieses Buch enthält ausreichend Übungsaufgaben, um verschiedene Aufgabentypen kennenzulernen und erfolgreich zu lösen. Die Themengebiete reichen von der Einheitenumrechnung über Bindungen, Reaktionen und Periodensystem bis zu Säuren, Basen, Energie und Co. Ausführliche Erläuterungen Lösungen ermöglichen es, auch schwierige Aufgaben nachzuvollziehen und so endlich zu verstehen. Die nächste Prüfung kann also kommen.
Author: Jill Barber
Publisher: Oxford University Press
Release Date: 2013-07-25
Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or treat life-threatening conditions such as HIV or cancer. Examining how drugs are manufactured, formulated, and the way that they work in our bodies, Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as it is applied to the study and practice of pharmacy. FEATURES * Supports an integrated pharmacy education * Focuses on the fundamental ideas that first-year students need to fully grasp before progressing in their studies * Demonstrates the connections between scientific concepts and principles and how they are applied to pharmacy * Written and edited by experts who have a wealth of teaching experience COMPANION WEBSITE For registered adopters of the book: - Figures from the book, available to download For students: - Self-assessment questions for each chapter - Related additional resources ABOUT THE SERIES The Integrated Foundations of Pharmacy series supports those who are at the beginning of their journey to become a pharmacist. Students will begin to understand how a drug molecule is made; the process that turns it into a medicine; the role the pharmacist has when dispensing that medicine; and what happens in the body when it is taken. Most importantly, the series shows how each of these aspects are integrated, reflecting the most up-to-date teaching practices.
Author: James Huheey
Publisher: Walter de Gruyter GmbH & Co KG
Release Date: 2014-07-28
This modern textbook stands out from other standard textbooks. The framework for the learning units is based on fundamental principles of inorganic chemistry, such as symmetry, coordination, and periodicity. Specific examples of chemical reactions are presented to exemplify and demonstrate these principles. Numerous new illustrations, a new layout, and large numbers of exercises following each chapter round out this new edition.
For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership
Author: Peter C. Meier
Publisher: John Wiley & Sons
Release Date: 2005-03-04
This new edition of a successful, bestselling book continues toprovide you with practical information on the use of statisticalmethods for solving real-world problems in complex industrialenvironments. Complete with examples from the chemical andpharmaceutical laboratory and manufacturing areas, this thoroughlyupdated book clearly demonstrates how to obtain reliable results bychoosing the most appropriate experimental design and dataevaluation methods. Unlike other books on the subject, Statistical Methods inAnalytical Chemistry, Second Edition presents and solves problemsin the context of a comprehensive decision-making process under GMPrules: Would you recommend the destruction of a $100,000 batch ofproduct if one of four repeat determinations barely fails thespecification limit? How would you prevent this from happening inthe first place? Are you sure the calculator you are using istelling the truth? To help you control these situations, the newedition: * Covers univariate, bivariate, and multivariate data * Features case studies from the pharmaceutical and chemicalindustries demonstrating typical problems analysts encounter andthe techniques used to solve them * Offers information on ancillary techniques, including a shortintroduction to optimization, exploratory data analysis, smoothingand computer simulation, and recapitulation of errorpropagation * Boasts numerous Excel files and compiled Visual Basic programs-nostatistical table lookups required! * Uses Monte Carlo simulation to illustrate the variabilityinherent in statistically indistinguishable data sets Statistical Methods in Analytical Chemistry, Second Edition is anexcellent, one-of-a-kind resource for laboratory scientists andengineers and project managers who need to assess data reliability;QC staff, regulators, and customers who want to frame realisticrequirements and specifications; as well as educators looking forreal-life experiments and advanced students in chemistry andpharmaceutical science. From the reviews of Statistical Methods in Analytical Chemistry,First Edition: "This book is extremely valuable. The authors supply many veryuseful programs along with their source code. Thus, the user cancheck the authenticity of the result and gain a greaterunderstanding of the algorithm from the code. It should be on thebookshelf of every analytical chemist."-Applied Spectroscopy "The authors have compiled an interesting collection of data toillustrate the application of statistical methods . . . includingcalibrating, setting detection limits, analyzing ANOVA data,analyzing stability data, and determining the influence of errorpropagation."-Clinical Chemistry "The examples are taken from a chemical/pharmaceutical environment,but serve as convenient vehicles for the discussion of when to usewhich test, and how to make sense out of the results. Whilepractical use of statistics is the major concern, it is put intoperspective, and the reader is urged to use plausibilitychecks."-Journal of Chemical Education "The discussion of univariate statistical tests is one of the morethorough I have seen in this type of book . . . The treatment oflinear regression is also thorough, and a complete set of equationsfor uncertainty in the results is presented . . . The bibliographyis extensive and will serve as a valuable resource for thoseseeking more information on virtually any topic covered in thebook."-Journal of American Chemical Society "This book treats the application of statistics to analyticalchemistry in a very practical manner. [It] integrates PC computingpower, testing programs, and analytical know-how in the context ofgood manufacturing practice/good laboratory practice (GMP/GLP) . ..The book is of value in many fields of analytical chemistry andshould be available in all relevant libraries."-Chemometrics andIntelligent Laboratory Systems