Introduction to Pharmaceutical Chemical Analysis

Author: Steen Honor? Hansen
Publisher: John Wiley & Sons
ISBN: 9780470661215
Release Date: 2011-12-12
Genre: Medical

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Introduction to Pharmaceutical Chemical Analysis

Author: Steen Honor? Hansen
Publisher: John Wiley & Sons
ISBN: 9781119954330
Release Date: 2011-10-18
Genre: Science

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Introduction to Pharmaceutical Chemical Analysis

Author: Steen Honor? Hansen
Publisher: John Wiley & Sons
ISBN: 9780470661222
Release Date: 2011-12-12
Genre: Medical

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Pharmaceutical Analysis

Author: P. D. Chaithanya Sudha
Publisher: Pearson Education India
ISBN: 9788131799505
Release Date:
Genre:

Pharmaceutical Analysis is a compulsory subject offered to all the under graduate students of Pharmacy. This book on Pharmaceutical Analysis has been designed considering the syllabi requirements laid down by AICTE and other premier institutes/universities. The book covers both the Titrimetric and Instrumental aspects of Pharmaceutical analysis which is helpful for use in multiple semesters.

Pharmaceutical Analysis

Author: David G. Watson
Publisher: Elsevier Health Sciences
ISBN: 9780702069888
Release Date: 2015-12-24
Genre: Medical

Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on Biotech products. New chapter on electrochemical methods in diagnostics. Greatly extended chapter on molecular emission spectroscopy to accommodate developments and innovations in the area. Now on StudentConsult

Pharmaceutical Analysis for Small Molecules

Author: Behnam Davani
Publisher: John Wiley & Sons
ISBN: 9781119425014
Release Date: 2017-08-01
Genre: Science

A comprehensive introduction for scientists engaged in new drug development, analysis, and approvals Each year the pharmaceutical industry worldwide recruits thousands of recent science graduates—especially chemistry, analytical chemistry, pharmacy, and pharmaceutical majors—into its ranks. However, because of their limited background in pharmaceutical analysis most of those new recruits find making the transition from academia to industry very difficult. Designed to assist both recent graduates, as well as experienced chemists or scientists with limited regulatory, compendial or pharmaceutical analysis background, make that transition, Pharmaceutical Analysis for Small Molecules is a concise, yet comprehensive introduction to the drug development process and analysis of chemically synthesized, small molecule drugs. It features contributions by distinguished experts in the field, including editor and author, Dr. Behnam Davani, an analytical chemist with decades of technical management and teaching experience in compendial, regulatory, and industry. This book provides an introduction to pharmaceutical analysis for small molecules (non-biologics) using commonly used techniques for drug characterization and performance tests. The driving force for industry to perform pharmaceutical analyses is submission of such data and supporting documents to regulatory bodies for drug approval in order to market their products. In addition, related required supporting studies including good laboratory/documentation practices including analytical instrument qualification are highlighted in this book. Topics covered include: Drug Approval Process and Regulatory Requirements (private standards) Pharmacopeias and Compendial Approval Process (public standards) Common methods in pharmaceutical analysis (typically compendial) Common Calculations for assays and impurities and other specific tests Analytical Method Validation, Verification, Transfer Specifications including how to handle out of specification (OOS) and out of trend (OOT) Impurities including organic, inorganic, residual solvents and elemental impurities Good Documentation Practices for regulatory environment Management of Analytical Laboratories Analytical Instrument Qualifications including IQ, OQ, PQ and VQ Due to global nature of pharmaceutical industry, other topics on both regulatory (ICH) and Compendial harmonization are also highlighted. Pharmaceutical Analysis for Small Molecules is a valuable working resource for scientists directly or indirectly involved with the drug development process, including analytical chemists, pharmaceutical scientists, pharmacists, and quality control/quality assurance professionals. It also is an excellent text/reference for graduate students in analytical chemistry, pharmacy, pharmaceutical and regulatory sciences.

Analysis Removal Effects and Risk of Pharmaceuticals in the Water Cycle

Author:
Publisher: Elsevier
ISBN: 0080549705
Release Date: 2007-10-10
Genre: Science

Pharmaceutically active substances are a class of new, so-called "emerging" contaminants that have raised great concern in recent years. Human and veterinary drugs are constantly being introduced into the environment, mainly as a result of the manufacturing process. Over time, this level of chemical input may lead to long-term concentrations and promote continual, but unnoticed adverse effects on aquatic and terrestrial organisms. Analysis, Fate and Removal of Pharmaceuticals in the Water Cycle discusses state-of-the-art analytical methods for trace determination of pharmaceuticals in environmental samples while reviewing the fate and occurrence of pharmaceuticals in the water cycle (elimination in wastewater and drinking water treatment). Focus is given to the newest developments in the treatment technologies, such as membrane bioreactors and advance oxidation processes. * Well-structured overview of latest developments in trace determination * Concise and critical compilation of literature published over the past few years * Focuses on new treatment technologies, such as membrane bioreactors and advance oxidation processes.

Practical Pharmaceutical Chemistry

Author: A. H. Beckett
Publisher: A&C Black
ISBN: 0485113236
Release Date: 1988
Genre: Science

This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.

Reviews in Pharmaceutical and Biomedical Analysis

Author: Paraskevas D. Tzanavaras
Publisher: Bentham Science Publishers
ISBN: 9781608051908
Release Date: 2010-01-01
Genre: Science

Reviews in Pharmaceutical and Biomedical Analysis - Reviews in Pharmaceutical and Biomedical Analysis contains coverage and review of new trends and applications in all areas of pharmaceutical, biomedical and analytical chemistry. Authors have contributed review articles according to their expertise on various relevant topics. The book's aim is to cover important instrumental analytical methods that are applied to the analysis of compounds with pharmaceutical and biomedical interest, including liquid and gas chromatography, electrophoresis & related techniques, mass spectrometry, hyphenated techniques, automated analytical techniques, spectrometry, luminescence, electroanalysis etc. Since the analysis of pharmaceuticals in a variety of matrices (formulations, biological material, environmental samples) is and will continue to be a "hot" topic, such a review book will be of interest to a very broad spectrum of scientists involved in chemistry and medicine.

Essentials of Pharmaceutical Chemistry

Author: Donald Cairns
Publisher: Pharmaceutical Press
ISBN: 9780853699798
Release Date: 2012-01-01
Genre: Medical

An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems. The 4th edition includes new chapters on Chromatographic Methods of Analysis, and Medicinal Chemistry - The Science of Drug Design.

Novel Developments in Pharmaceutical and Biomedical Analysis

Author: Atta-ur- Rahman
Publisher: Bentham Science Publishers
ISBN: 9781681085746
Release Date: 2018-04-24
Genre: Science

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds.

Method Validation in Pharmaceutical Analysis

Author: Joachim Ermer
Publisher: John Wiley & Sons
ISBN: 9783527672189
Release Date: 2014-08-27
Genre: Medical

This second edition of a global bestseller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (QbD) and lifecycle concepts in pharmaceutical manufacturing. As in the first edition, the fundamental requirements for analytical method validation are covered, but the second edition describes how these are applied systematically throughout the entire analytical lifecycle. QbD principles require adoption of a systematic approach to development and validation that begin with predefined objectives. For analytical methods these predefined objectives are established as an Analytical Target Profile (ATP). The book chapters are aligned with recently introduced standards and guidelines for manufacturing processes validation and follow the three stages of the analytical lifecycle: Method Design, Method Performance Qualification, and Continued Method Performance Verification. Case studies and examples from the pharmaceutical industry illustrate the concepts and guidelines presented, and the standards and regulations from the US (FDA), European (EMA) and global (ICH) regulatory authorities are considered throughout. The undisputed gold standard in the field.

Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products

Author: M.M.W.B. Hendriks
Publisher: Elsevier
ISBN: 0080540635
Release Date: 1996-12-11
Genre: Technology & Engineering

In analytical chemistry and pharmaceutical technology attention is increasingly focussed on improving the quality of methods and products. This book aims at fostering the awareness of the potential of existing mathematical and statistical methods to improve this quality. It provides procedures and ideas on how to make a product or a method less sensitive to small variations in influencing factors. Major issues covered are robustness and stability improvement and ruggedness testing. General strategies and a theoretical introduction to these methods are described, and thorough overviews of methods used in both application areas and descriptions of practical applications are given. Features of this book: • Gives a good overview of mathematical and statistical methods used in two application areas, i.e. pharmaceutical technology and analytical chemistry • Illustrates the different approaches available to attain robustness • Gives ideas on how to use methods in practical situations. The book is intended for those who develop and optimize, and are responsible for the overall quality of, analytical methods and pharmaceutical technological products and procedures.

An Introduction to Medicinal Chemistry

Author: Graham Patrick
Publisher: Oxford University Press
ISBN: 9780198749691
Release Date: 2017
Genre: Pharmaceutical chemistry

For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?An Introduction to Medicinal Chemistry, sixthedition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Inaddition to covering the key principles of drug design and drug action, the text also discusses important current topics in medicinal chemistry. The subject is brought to life throughout by engaging case studies highlighting particular classes of drugs, and the stories behind their discovery and development.