Iron and Blood

Author: Gail Z. Martin
Publisher: Solaris
ISBN: 9781849979177
Release Date: 2015-07-02
Genre: Fiction

New Pittsburgh, 1898 – a crucible of invention and intrigue. Born from the ashes of devastating fire, flood and earthquake, the city is ruled by the shadow government of The Oligarchy. In the swarming streets, people of a hundred nations drudge to feed the engines of progress, while in the abandoned tunnels beneath the city, supernatural creatures hide from the light, emerging only to feed. Jake Desmet and Rick Brand travel the world to secure treasures and unusual items for the collections of wealthy patrons, accompanied by Jake’s cousin, Veronique LeClerque. But when their latest commission leads to Jake’s father’s murder, the three friends are drawn into a conspiracy where dark magic, industrial sabotage and the monsters that prey on the night will ultimately threaten not just New Pittsburgh, but the whole world.

Iron and Blood

Author: Henry Heller
Publisher: McGill-Queen's Press - MQUP
ISBN: 0773508163
Release Date: 1991-02-01
Genre: History

Heller refutes Roland Mousnier's thesis that early modern France was a society of orders in which most people knew and accepted their status in society. This concept of order certainly had meaning for the sixteenth-century élite because of aristocratic domination over land and people, but it is not clear that this was also the view of the commoners. Heller maintains that for peasants, craftsmen, and merchants the decline of the French economy started at the beginning rather than the middle of the sixteenth century. This resulted in unrest which spread from town to countryside, culminating in the three great popular movements of the civil wars: the Calvinist Revolt of the 1560s, the Catholic League's challenge to the power of the Monarchy, and the revolts of the 1590s. Heller stresses that the history of sixteenth-century France is one of both resistance and domination. It was often the upper class which took the initiative, directing much of the violence toward the commoners, and many of those involved in the civil wars were fighting for their own economic positions. Iron and Blood helps to clarify the significance of the French Civil Wars by showing them to be rooted in an aristocratic reaction against the earlier social unrest which began among the common people.

Blood and Iron

Author: Elizabeth Bear
Publisher: Penguin
ISBN: 0451462173
Release Date: 2008
Genre: Fiction

Seeker, a woman enchanted by the Faerie Queen and forced to kidnap human children for the pleasure of her mistress, goes after her latest prey, a Merlin, a child possessing a limitless magic that could tip the ultimate balance of power. Reprint.

Iron and Blood

Author: Joshua Dalzelle
Publisher: Createspace Independent Publishing Platform
ISBN: 1542870356
Release Date: 2017-01-31
Genre:

The Black Fleet Saga continues... A human planet has been invaded. The enigmatic Darshik have landed troops on a frontier world and have begun subduing major cities even as their blockade repels all attempts by the fledgling United Terran Federation to mount a counteroffensive. The Federation's military command is desperate and with their fleet still in tatters they make a last ditch effort to free the planet: They pull Captain Jackson Wolfe out of retirement and put him in command of a ship they hope can get past the defending armada and provide support to the beleaguered Marines and civilians fighting on the surface of the contested world. There is no reasoning with this enemy. If the Terran Federation wants their planet back, they will have to pay the price. Iron & Blood is the second book of The Expansion Wars Trilogy and the fifth book of the Black Fleet Saga.

Blood Iron and Gold

Author: Christian Wolmar
Publisher: PublicAffairs
ISBN: 9781586488512
Release Date: 2010-03-02
Genre: Transportation

The opening of the Liverpool and Manchester Railway in 1830 marked the beginning of a transport revolution that would forever transform the way we live. Blood, Iron, and Gold takes us on a journey encompassing jungle, mountain, and desert, revealing the huge impact of the railroads as they spread rapidly across entire countries, and linked cities that hitherto had little reach beyond their immediate environs. The rise of the train triggered daring engineering feats, great architectural innovation, and the rapid movement of people and goods across the globe. Cultures were both enriched and destroyed by the unrelenting construction of the railroads, and the new technology quickly took on a vital role in civil conflicts and two world wars. In this beautifully illustrated book, renowned transportation journalist Christian Wolmar celebrates the vision and determination of the ambitious pioneers who developed the railways that would dominate the globe.

Iron and Blood

Author: Auston Habershaw
Publisher: HarperCollins
ISBN: 9780062369178
Release Date: 2015-06-02
Genre: Fiction

Part II of the Saga of the Redeemed picks up right where The Iron Ring left off … After Tyvian Reldamar gets double-crossed by his business partner, he is affixed with an iron ring that prevents the wearer from any evildoing. Not one to be deterred by this setback, he quickly puts into motion a plan for revenge—one that will use every dirty trick in the book. But things are never simple for mastermind Tyvian, especially not after he uncovers a sinister plot: evil wizard Banric Sahand is planning to decimate the city of Freegate. Now Tyvian must learn to work with—and rely on—his motley crew of accomplices, including an adolescent pickpocket, an obese secret-monger, a fearsome gnoll, and a Mage Defender…who is also trying to get him arrested. Time is running out for Tyvian's plan for revenge—while the fate of the city hangs in the balance.

Iron Axe

Author: Steven Harper
Publisher: Penguin
ISBN: 9780698146297
Release Date: 2015-01-06
Genre: Fiction

In this brand new series from the author of the Clockwork Empire series, a hopeless outcast must answer Death’s call and embark on an epic adventure.... Although Danr’s mother was human, his father was one of the hated Stane, a troll from the mountains. Now Danr has nothing to look forward to but a life of disapproval and mistrust, answering to “Trollboy” and condemned to hard labor on a farm. Until, without warning, strange creatures come down from the mountains to attack the village. Spirits walk the land, terrifying the living. Trolls creep out from under the mountain, provoking war with the elves. And Death herself calls upon Danr to set things right. At Death’s insistence, Danr heads out to find the Iron Axe, the weapon that sundered the continent a thousand years ago. Together with unlikely companions, Danr will brave fantastic and dangerous creatures to find a weapon that could save the world—or destroy it.

Iron and Blood

Author: Brad Farley
Publisher: Lulu.com
ISBN: 9781329136212
Release Date: 2015-05-14
Genre: Fiction

The Iron Kingdom: a half-mythical land conquered by barbarians an age ago, celebrated in song and legend. Here is a land of contrasts as beauty and savagery collide. The north-men, now savages no more, struggle to leave their brutal past behind as they strive to become more civilized and find peace. Yet, it remains a land of conflict ruled over by the Iron King, a mighty ruler, who is himself something of a legend. However, the king has grown old and the sun is setting on the days of his saga. Shadows grow long in the south, and Lord Garyth, a nobleman of doubtful lineage and agent of the crown is returning home...

I Am Canada Blood and Iron

Author: Paul Yee
Publisher: Scholastic Canada
ISBN: 9781443119269
Release Date: 2012-01-01
Genre: Juvenile Fiction

The incredible sacrifices made by Chinese workers building the transcontinental railway are revealed in this powerful novel. Heen's father and grandfather have brought their family in China to the brink of ruin with their gambling habits. To solve their money troubles, Heen and his father come to Canada to build the railway - a decision plagued by disaster. The living conditions provided for workers are wretched and work on the railway is excruciating. Transporting tons of gravel and working in tunnels about to be dynamited proves to be deadly for many of his co-workers. Soon the friction between the Chinese workers and the whites, who barely acknowledge these deaths, reaches a fevered pitch. As an added stress, Heen's father has found some men to gamble with, which puts all of their earnings at risk. Heen's only solace is his journal, where his chilling observations of the injustice and peril heaped upon the workers serve as an important testament to this dramatic era in Canadian history.

Blood and Iron

Author: Jon Sprunk
Publisher: Prometheus Books
ISBN: 9781616148942
Release Date: 2014-03-11
Genre: Fiction

This action-heavy EPIC FANTASY SERIES OPENER is like a sword-and-sorcery Spartacus set in a richly-imagined world. It starts with a shipwreck following a magical storm at sea. Horace, a soldier from the west, had joined the Great Crusade against the heathens of Akeshia after the deaths of his wife and son from plague. When he washes ashore, he finds himself at the mercy of the very people he was sent to kill, who speak a language and have a culture and customs he doesn't even begin to understand. Not long after, Horace is pressed into service as a house slave. But this doesn't last. The Akeshians discover that Horace was a latent sorcerer, and he is catapulted from the chains of a slave to the halls of power in the queen's court. Together with Jirom, an ex-mercenary and gladiator, and Alyra, a spy in the court, he will seek a path to free himself and the empire's caste of slaves from a system where every man and woman must pay the price of blood or iron. Before the end, Horace will have paid dearly in both. From the Trade Paperback edition.

Blood and Iron

Author: Otto Friedrich
Publisher: HarperCollins Publishers
ISBN: UOM:39015038410240
Release Date: 1995
Genre: Germany

A chronicle of more than a century of German history focuses on the role played in that history by the Von Moltke family, from a field marshall who won the Franco-Prussian War to a count whom the Gestapo executed for conspiracy. National ad/promo.

Blood and Iron

Author: Tony Ballantyne
Publisher: Pan Macmillan
ISBN: 9780230753709
Release Date: 2011-03-04
Genre: Fiction

Appointed Commander of the Emperor’s Army of Sangrel, Wa-Ka-Mo-Do of Ko tries to establish relations between the existing robot population and the humans who have recently arrived on Yukawa. On the continent of Shull, Kavan forms the Uncertain Army and is marching to Artemis City. Upon discovery that the city’s generals have made an alliance with the humans, he retreats to Stark where he plans the eventual overthrow of Artemis and the humans. Meanwhile, Karel is heading South, hoping to be reunited with Susan, his wife. As he walks, he hears more of the stories of the robots, and begins to understand something about his place on the world of Penrose. But with limited resources and tensions growing between robot and human it’s only a matter of time before problems arise. And it’s becoming more and more apparent that the humans are a lot more powerful than the robots first expected . . .

Portals of Iron and Blood

Author: R. L. Haas
Publisher: Createspace Independent Publishing Platform
ISBN: 1541037642
Release Date: 2016-12-20
Genre:

It was the knock on Naya's front door that would change her life forever. Again. What would you do if you unexpectedly came face-to-face with your past and your future? The last time Naya ventured into the Colorado woods, she discovered her Fae heritage and met the man whose face had haunted her dreams. But this time, the answers she seeks lie with the seemingly mortal man who wears her dead husband's face and the magical artifact that pulses where her soul once dwelled. In a race against time, Naya, Irena, and Harris seek the elusive answers to Tian's death and what his doppelganger Wyatt's presence could mean - for them, and for the fate of Alonthiel.

Structural Dependency of Iron and Blood mediated Degradation and Heme Alkylation for a Series of Novel Ozonides

Author: Lukas Stingelin
Publisher:
ISBN: OCLC:1011508638
Release Date: 2012
Genre:

Malaria is a devastating disease prevalent in (sub)tropical regions and causes considerable morbidity and mortality. Infection is caused by the hematoprotozoan Plasmodium parasite and transmitted by female anopheline mosquitoes. Drug therapy is critical for the treatment of malaria, however many well-established antimalarial drugs have become ineffective due to parasite resistance. Newer treatments, such as artemisinin combination therapies, are highly effective, but cost, availability and poor biopharmaceutical properties hamper their utility. Alarming reports have also suggested that resistance to the artemisinins may be emerging. A new class of fully synthetic antimalarial compounds, the 1,2,4-trioxolanes or ozonides, overcome many of the limitations seen with the artemisinins, and two compounds of this class, OZ277 and OZ439, have advanced to clinical trials.There is still controversy surrounding the mechanism of action of peroxide antimalarials. The peroxide is required for activity, and many investigators believe that it is activated in the presence of high concentrations of iron(II) species liberated upon hemoglobin digestion within the parasite. Radical species formed are then thought to alkylate parasite targets, leading to parasite death. Peroxides are known to be unstable in environments rich in iron(II), suggesting a link between the processes leading to peroxide degradation and those required for activation and ultimately, antimalarial activity. Based upon this fundamental hypothesis, the goals of this thesis were to characterize the stability and partitioning of representative peroxide antimalarials, to define structural trends in iron- and blood-mediated degradation, to further confirm the link between heme alkylation and biological activity and to elucidate some of the mechanisms involved in these degradation processes and link these to the proposed mechanisms of action.Using a selection of ozonides across a wide range of structures and antimalarial activity, clear structural relationships were defined for their stability in iron(II) sulphate solutions as well as in a biologically-relevant blood-like matrix. Previous correlations between the extent of heme alkylation and in vitro potency were confirmed using the more extensive and structurally diverse set of compounds.Partitioning and degradation studies with OZ277 (as a model ozonide) in a blood-like matrix demonstrated that the degradation rate depended on hematocrit, parasitemia, and compound concentration. Using structurally diverse compounds, there was no evidence of selective accumulation in infected erythrocytes under the conditions used, and degradation increased significantly in infected compared to non-infected blood.Blood-mediated degradation of OZ277 was substantially reduced in presence of an iron chelating agent suggesting a role of chelatable iron which was further supported by the correlation between iron- with blood-mediated degradation. Conversely, the chelating agent only partially reduced the degradation rate in infected blood, indicating additional degradation mechanisms (possibly linked to the mechanism of action). The reduced recovery of one of the metabolites, adamantane lactone, in infected blood is also consistent with this hypothesis.OZ277 rapidly and extensively degraded with digested hemoglobin, but was stable in the presence of non-degraded hemoglobin. This degradation was unaffected by inclusion of the iron chelator, but was completely eliminated in presence of an oxidizing agent. These results are consistent with non-chelatable iron(II) heme released upon hemoglobin digestion being at least partly responsible for OZ277 degradation in infected blood. These studies provide further insight into biological processes related to iron-mediated reactivity of this novel series of compounds.