Molecular Imaging I

Author: Wolfhard Semmler
Publisher: Springer Science & Business Media
ISBN: 9783540727187
Release Date: 2008-07-15
Genre: Medical

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Emerging Applications of Molecular Imaging to Oncology

Author:
Publisher: Elsevier
ISBN: 9780124116344
Release Date: 2014-09-27
Genre: Science

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume, number 124, covers emerging applications of molecular imaging to oncology, including molecular-genetic imaging, imaging the tumor microenvironment, tracking cells and vaccines in vivo, and more. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Molecular Imaging II

Author: Wolfhard Semmler
Publisher: Springer Science & Business Media
ISBN: 9783540774969
Release Date: 2008-07-15
Genre: Medical

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Biomedical Imaging

Author: Martin Braddock
Publisher: Royal Society of Chemistry
ISBN: 9781849730143
Release Date: 2011
Genre: Medical

The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.

MRT in der Gastroenterologie

Author: Henning E. Adamek
Publisher: Georg Thieme Verlag
ISBN: 3131492910
Release Date: 2010
Genre: Gastrointestinale Krankheit - NMR-Tomographie - Lehrbuch


Grainger Allison s Diagnostic Radiology E Book

Author: Andy Adam
Publisher: Elsevier Health Sciences
ISBN: 9780702061288
Release Date: 2014-06-16
Genre: Medical

Effectively apply the latest techniques and approaches with complete updates throughout including 4 new sections (Abdominal Imaging, The Spine, Oncological Imaging, and Interventional Radiology) and 28 brand new chapters. Gain the fresh perspective of two new editors—Jonathan Gillard and Cornelia Schaefer-Prokop -- eight new section editors -- Michael Maher, Andrew Grainger, Philip O’Connor, Rolf Jager, Vicky Goh, Catherine Owens, Anna Maria Belli, Michael Lee -- and 135 new contributors. Stay current with the latest developments in imaging techniques such as CT, MR, ultrasound, and coverage of hot topics such as: Image guided biopsy and ablation techniques and Functional and molecular imaging. Solve even your toughest diagnostic challenges with guidance from nearly 4,000 outstanding illustrations. Quickly grasp the fundamentals you need to know through a more concise, streamlined format.

Magnetresonanzbildgebung

Author: Marinus T. Vlaardingerbroek
Publisher: Springer-Verlag
ISBN: 9783642186974
Release Date: 2013-03-08
Genre: Science

Das bekannte Lehrbuch zur Physik und Technik der kernmagnetischen Resonanz liegt jetzt auch in deutscher Sprache vor. Es beschreibt den physikalischen Hintergrund der Scan-Methoden und ihren Einsatz in der medizinischen Diagnostik. In diesem Zusammenhang werden auch neue Wege und Verfahren aufgezeigt. Besondere Aufmerksamkeit gilt der Behandlung von Artefakten und ihrer mathematischen Beschreibung. Das Buch ist mit vielen Illustrationen zu Scan-Verfahren, wie z.B. RARE, GRASE, EPI, Balanced FFE und Spiralscan ausgestattet. Detaillierte Aussagen über Echoamplituden in Multi-Echosequenzen, wie TSE, FFE und BURST sind in einem besonderen Kapitel mit Hilfe der Konfigurationstheorie ausführlich abgehandelt. Eine kurze Einführung in die Geschichte der MR-Bildgebung rundet dieses Buch ab.

Molecular Imaging

Author: Ralph Weissleder
Publisher: PMPH-USA
ISBN: 1607950057
Release Date: 2010
Genre: Medical

The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Biosensors and Biodetection

Author: Avraham Rasooly
Publisher: Humana PressInc
ISBN: UOM:39015075645500
Release Date: 2009
Genre: Medical

Biosensors combine biological recognition elements and signal conversion elements into a biodetection system. This book describes the major technologies in the field in extensive technical detail, providing a user-friendly guide to this vital technology.

Antipsychotics

Author: John G. Csernansky
Publisher: Springer Science & Business Media
ISBN: 9783642610073
Release Date: 2012-12-06
Genre: Medical

Antipsychotic drugs were first discovered in 1953, and not since the late 1970s has the Handbook of Experimental Pharmacology taken up this topic. A new treatment of this topic would be due under any circumstances; however, this is now particularly true, since remarkable progress has been made on several fronts in furthering our understanding of the mechanisms of antipsychotic drug action. First, we have learned that schizophrenia is an illness with particu lar neuroanatomical abnormalities, many of which suggest that the illness is caused by errors in neurodevelopment. These findings have helped to form a context for understanding neurochemical aberrations in the illness and suggest new approaches for pharmacological treatment. Propelled forward by rapid advances in neurochemical anatomy, current pathophysiological hypotheses of schizophrenia and antipsychotic drug action have taken on the appearance of complex electrical circuit diagrams. Second, molecular biology studies have now revealed that there is a multiplicity of dopamine receptors (i. e. , D , DZshort' j DZlong, D , D , and D ), some of which may become entirely new targets for 3 4 s antipsychotic drug action. Ironically, the development of drugs that are selec tive for these receptors and that can be used to investigate their function lags behind; yet the discovery of these new receptors offers unparalleled opportu nities for developing drugs with improved efficacy and fewer side effects.

Characterization of lignocellulosic materials

Author: Thomas Q. Hu
Publisher: Wiley-Blackwell
ISBN: 1405158808
Release Date: 2008
Genre: Science

Lignocellulosic materials are a natural, abundant and renewable resource essential to the functioning of industrial societies and critical to the development of a sustainable global economy. As wood and paper products, they have played an important role in the evolution of civilization. Improvement of the quality and manufacturing efficiency of such products has often been hampered by the lack of understanding of the complex structures and chemical compositions of the materials. Due to increasing economic and environmental issues concerning the use of petrochemicals, lignocellulosic materials will be relied upon as feedstock for the production of chemicals, fuels and biocompatible materials. Significant progress has been made to use lignocellulosic materials for the production of fuel ethanol and as a reinforcing component in polymer composites. Effective and economical methods for such uses, however, remain underdeveloped, partly due to the difficulties encountered in the characterization of the structures of native lignocelluloses and lignocelluloses-based materials. Improved methods for the characterization of lignocellulosic materials are needed. Characterization of Lignocellulosic Materials covers recent advances in the characterization of wood, pulp fibres and papers. It also describes the analyses of native and modified lignocellulosic fibres and materials using a range of advanced techniques such as time-of-flight secondary ion mass spectrometry, 2D heteronuclear single quantum correlation NMR, and Raman microscopy. The book provides a survey of state-of-the-art characterization methods for lignocellulosic materials, for both academic and industrial researchers who work in the fields of wood and paper, lignocelluloses-based composites and polymer blends, and bio-based fuels and materials.

Molecular and Cellular MR Imaging

Author: Michel M.J. Modo
Publisher: CRC Press
ISBN: 1420004093
Release Date: 2007-03-28
Genre: Medical

The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gene expression in living subjects is rapidly moving from the research laboratory into daily clinical settings. The interdisciplinary nature of the field mandates a constant dialogue among molecular and cellular biology, chemistry, physics, image analysis, and drug discovery to develop and translate promising approaches into reliable scientific applications and viable clinical diagnostic tools. Bringing together a select panel of internationally recognized authors, Molecular and Cellular MR Imaging provides a state-of-the-science overview of the multidisciplinary nature of the field and illustrates the application of these various sciences to investigate specific biological processes in animals and humans. Using a systematic organization to present diverse information, the text begins with an introductory chapter that defines cellular and molecular imaging and explains why magnetic resonance imaging (MRI) is the most versatile approach for noninvasive, in vivo studies. The first section examines the physicochemical principles of various contrast agents including paramagnetic, superparamagnetic, CEST, and PARACEST agents, as well as smart and sensing agents. The second section summarizes the wide variety of applications for molecular imaging of genes and of disease states. Contributions cover cancer, apoptosis, cardiovascular and neurodegenerative disease, and the use of pharmacological MRI. The third section is devoted to cellular imaging under a variety of applications, and the final section discusses the translational aspects and future directions of cellular and molecular MR imaging. Molecular and Cellular MR Imaging highlights the diversity of skills required to translate advancements in various fields of research into practical applications that promise to revolutionize in vivo imaging as a diagnostic tool.