Author: Wolfhard Semmler
Publisher: Springer Science & Business Media
Release Date: 2008-07-15
The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume, number 124, covers emerging applications of molecular imaging to oncology, including molecular-genetic imaging, imaging the tumor microenvironment, tracking cells and vaccines in vivo, and more. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students
Author: Martin Braddock
Publisher: Royal Society of Chemistry
Release Date: 2011
The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.
The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
Author: Andy Adam
Publisher: Elsevier Health Sciences
Release Date: 2014-06-16
Effectively apply the latest techniques and approaches with complete updates throughout including 4 new sections (Abdominal Imaging, The Spine, Oncological Imaging, and Interventional Radiology) and 28 brand new chapters. Gain the fresh perspective of two new editors—Jonathan Gillard and Cornelia Schaefer-Prokop -- eight new section editors -- Michael Maher, Andrew Grainger, Philip O’Connor, Rolf Jager, Vicky Goh, Catherine Owens, Anna Maria Belli, Michael Lee -- and 135 new contributors. Stay current with the latest developments in imaging techniques such as CT, MR, ultrasound, and coverage of hot topics such as: Image guided biopsy and ablation techniques and Functional and molecular imaging. Solve even your toughest diagnostic challenges with guidance from nearly 4,000 outstanding illustrations. Quickly grasp the fundamentals you need to know through a more concise, streamlined format.
Das bekannte Lehrbuch zur Physik und Technik der kernmagnetischen Resonanz liegt jetzt auch in deutscher Sprache vor. Es beschreibt den physikalischen Hintergrund der Scan-Methoden und ihren Einsatz in der medizinischen Diagnostik. In diesem Zusammenhang werden auch neue Wege und Verfahren aufgezeigt. Besondere Aufmerksamkeit gilt der Behandlung von Artefakten und ihrer mathematischen Beschreibung. Das Buch ist mit vielen Illustrationen zu Scan-Verfahren, wie z.B. RARE, GRASE, EPI, Balanced FFE und Spiralscan ausgestattet. Detaillierte Aussagen über Echoamplituden in Multi-Echosequenzen, wie TSE, FFE und BURST sind in einem besonderen Kapitel mit Hilfe der Konfigurationstheorie ausführlich abgehandelt. Eine kurze Einführung in die Geschichte der MR-Bildgebung rundet dieses Buch ab.
Author: James C. Dabrowiak
Release Date: 2009-12-21
Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed. These chapters lay the groundwork, in order that students can clearly understand how agents work, whatever their subject background. Following this introduction, chapters focus on individual metallo-drugs and agents for treating and detecting disease, their synthesis, structure and general properties, known mechanism of action and important physical and chemical principles that apply. Topics covered include cisplatin; platinum anticancer drugs; ruthenium, titanium, and gallium for treating cancer; gold compounds for treating arthritis, cancer, and other diseases; vanadium, copper, and zinc in medicine; metal complexes for diagnosing disease; and metals in nanomedicine. Throughout the book, “Feature Boxes” expand on features of drugs that are not directly related to studying metals in medicine, for example discovery, medical use, specialist assays, and metals in biology. At the end of the chapters there are specifically designed problems/exercises that apply basic kinetic, thermodynamic and chemical principles to practical problem solving in metals in medicine. Metals in Medicine distils the essence of this important topic for undergraduate and graduate students in chemistry, biochemistry, biology and the related areas of biophysics, pharmacology, and bioengineering, and for researchers in other fields interested in getting a general insight into metals in medicine.
Author: Wolfgang Mohnike
Release Date: 2007-07-03
Synthese aus praxisrelevanten Informationen, beruhend auf eigenen Erfahrungen, kombiniert mit Literatur- und Studiendaten. Einmalig im deutschsprachigen Raum: Dieses Werk ermöglicht Praktikern, Lehrenden, Lernenden und interessierten Betroffenen den fundierten Einblick in die diagnostischen Möglichkeiten der PET/CT. Mit umfangreicher ausgewählter Fachliteratur, geeignet als Nachschlagewerk und Lehrbuch. Dieser Atlas bietet Orientierung über das einzigartige bildgebende Diagnoseverfahren - basierend auf dem Stoffwechsel der Krebszelle. Plus: CD-ROM mit noch mehr PET/CT-Bildern und vollständiger Bibliographie der ca. 15.000 Literaturstellen.
Author: Thomas Q. Hu
Release Date: 2008
Lignocellulosic materials are a natural, abundant and renewable resource essential to the functioning of industrial societies and critical to the development of a sustainable global economy. As wood and paper products, they have played an important role in the evolution of civilization. Improvement of the quality and manufacturing efficiency of such products has often been hampered by the lack of understanding of the complex structures and chemical compositions of the materials. Due to increasing economic and environmental issues concerning the use of petrochemicals, lignocellulosic materials will be relied upon as feedstock for the production of chemicals, fuels and biocompatible materials. Significant progress has been made to use lignocellulosic materials for the production of fuel ethanol and as a reinforcing component in polymer composites. Effective and economical methods for such uses, however, remain underdeveloped, partly due to the difficulties encountered in the characterization of the structures of native lignocelluloses and lignocelluloses-based materials. Improved methods for the characterization of lignocellulosic materials are needed. Characterization of Lignocellulosic Materials covers recent advances in the characterization of wood, pulp fibres and papers. It also describes the analyses of native and modified lignocellulosic fibres and materials using a range of advanced techniques such as time-of-flight secondary ion mass spectrometry, 2D heteronuclear single quantum correlation NMR, and Raman microscopy. The book provides a survey of state-of-the-art characterization methods for lignocellulosic materials, for both academic and industrial researchers who work in the fields of wood and paper, lignocelluloses-based composites and polymer blends, and bio-based fuels and materials.
Author: Avraham Rasooly
Publisher: Humana PressInc
Release Date: 2009
Biosensors combine biological recognition elements and signal conversion elements into a biodetection system. This book describes the major technologies in the field in extensive technical detail, providing a user-friendly guide to this vital technology.