Staphylococcus

Author: Jodi A. Lindsay
Publisher: Horizon Scientific Press
ISBN: 9781904455295
Release Date: 2008
Genre: Science

Focusing on the staphylococcal genetics, this title brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the-art overview of the field.

The Genetic Manipulation of Staphylococci

Author: Jeffrey L. Bose
Publisher:
ISBN: 149393158X
Release Date: 2016
Genre: Gene expression

This detailed book contains chapters using unbiased approaches such as chemical and transposon mutagenesis, as well as a protocol for allelic exchange, to make targeted mutants in Staphylococcus, as generating mutants of this bacteria can be accomplished in many ways, depending on the intended changes. Using these methods, the authors have been successful at making mutants that span individual single-nucleotide changes in the chromosome to whole genome mutant libraries. The latter strategy provides a useful tool for high-throughput screening, while single nucleotide changes are an elegant way of teasing apart the importance of single nucleotides in gene expression or to create specific amino acid substitutions to examine protein function. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, The Genetic Manipulation of Staphylococci: Methods and Protocols serves as a vital resource and guide to scientists in the Staphylococcus community as they pursue their studies on these bacteria.

Genetics and Evolution of Infectious Diseases

Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 9780128001530
Release Date: 2017-01-12
Genre: Medical

Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

Molecular Typing in Bacterial Infections

Author: Ivano Filippis
Publisher: Springer Science & Business Media
ISBN: 9781627031851
Release Date: 2012-11-07
Genre: Science

Molecular Typing in Bacterial Infections covers common bacterial pathogenic agents, with the most effective methods for their identification and classification in the light of their specific epidemiology. The book will be a valuable resource for molecular typing of infectious diseases agents encountered in both the research and hospital clinical lab settings, as well as culture collections. Each chapter provides an overview of molecular approaches to typing bacterial pathogens. Part I gives a general overview of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology. In Part II, the relative strengths and weaknesses of the different methods applicable to the specific agents of infectious diseases are emphasized. Specific emphasis is placed on recent changes and updates in molecular typing.

Staphylococci in Human Disease

Author: Kent B. Crossley
Publisher: John Wiley & Sons
ISBN: 1444308475
Release Date: 2009-10-13
Genre: Medical

Staphylococci remain the most important cause of hospital-acquired infections in the U.S. and MRSA has become the most common cause of skin and soft tissue infection in many parts of the world. There is now a much greater understanding of the physiology and evolution of the staphylococci and this new edition reflects the rapid advancements in knowledge about this pathogen and provides a comprehensive review from both clinical and basic science perspectives. The first section addresses the basic biology of the staphylococci, their molecular genetics, host defenses and host evasion, virulence determinants, mechanisms of antibiotic resistance, and laboratory techniques. The second section deals with epidemiology, and the third section provides an overview of the varied clinical manifestations of human staphylococcal infections. The fourth section covers prevention and treatment of these often life-threatening infections. Written by experts from around the globe, this book is essential reading for all clinicians and basic scientists studying the staphylococci.

Food Borne Pathogens and Antibiotic Resistance

Author: Om V. Singh
Publisher: John Wiley & Sons
ISBN: 9781119139157
Release Date: 2017-01-30
Genre: Medical

Food is an essential means for humans and other animals to acquire the necessary elements needed for survival. However, it is also a transport vehicle for foodborne pathogens, which can pose great threats to human health. Use of antibiotics has been enhanced in the human health system; however, selective pressure among bacteria allows the development for antibiotic resistance. Foodborne Pathogens and Antibiotic Resistance bridges technological gaps, focusing on critical aspects of foodborne pathogen detection and mechanisms regulating antibiotic resistance that are relevant to human health and foodborne illnesses This groundbreaking guide: • Introduces the microbial presence on variety of food items for human and animal consumption. • Provides the detection strategies to screen and identify the variety of food pathogens in addition to reviews the literature. • Provides microbial molecular mechanism of food spoilage along with molecular mechanism of microorganisms acquiring antibiotic resistance in food. • Discusses systems biology of food borne pathogens in terms of detection and food spoilage. • Discusses FDA’s regulations and Hazard Analysis and Critical Control Point (HACCP) towards challenges and possibilities of developing global food safety. Foodborne Pathogens and Antibiotic Resistance is an immensely useful resource for graduate students and researchers in the food science, food microbiology, microbiology, and industrial biotechnology. About the Editor Om V. Singh, PhD, is an Associate Professor of Microbiology at the University of Pittsburgh, Bradford in Bradford, PA, USA.

Staphylococcus

Author: Greg A. Somerville
Publisher: Caister Academic Press
ISBN: 9781910190500
Release Date: 2016-10-15
Genre: Medical

In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Gram positive Pathogens

Author: Vincent A. Fischetti
Publisher: ASM Press
ISBN: 9781555813437
Release Date: 2006
Genre: Medical

Provides comprehensive coverage of all gram-positive pathogens, including genome data. Appeals to clinicians, infectious disease specialists, and instructors and students seeking a single reference source on gram-positive bacteria.

Staphylococcus

Author: Greg A. Somerville
Publisher: Caister Academic Press
ISBN: 9781910190500
Release Date: 2016-10-15
Genre: Medical

In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Molecular Genetic and Nutritional Aspects of Major and Trace Minerals

Author: James F Collins
Publisher: Academic Press
ISBN: 9780128023761
Release Date: 2016-09-14
Genre: Medical

Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace minerals Provides a broad introductory chapter on each mineral to give readers valuable background and context Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspects Includes coverage of all nutritionally relevant minerals—essential major trace minerals and ultra-trace minerals Underscores the important interactions between minerals so readers learn how metabolism of one mineral influences another

Mobile DNA III

Author: Nancy Lynn Craig
Publisher: Amer Society for Microbiology
ISBN: 1555819206
Release Date: 2015-05-15
Genre: Medical

This new edition of the bestselling series on movable genetic elements highlights the many exciting advances in the field over the last decade, including conservative site-specific recombination, programmed rearrangements, DNA-only transposons, and LTR, and non-LTR retrotransposons. Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, revealing the many important roles that mobile DNAs play in genome structure, function, and evolution. This book is part three of a series on mobile DNA. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Food Microbiology

Author: Michael P. Doyle
Publisher: American Society for Microbiology Press
ISBN: 9781555816261
Release Date: 2012-12-28
Genre: Science

This essential reference emphasizes the molecular and mechanistic aspects of food microbiology in one comprehensive volume. • Addresses the field's major concerns, including spoilage, pathogenic bacteria, mycotoxigenic molds, viruses, prions, parasites, preservation methods, fermentation, beneficial microorganisms, and food safety. • Details the latest scientific knowledge and concerns of food microbiology • Offers a description of the latest and most advanced techniques for detecting, analyzing, tracking, and controlling microbiological hazards in food. • Serves as significant reference book for professionals who conduct research, teach food microbiology courses, analyze food samples, conduct epidemiologic investigations, and craft food safety policies.

The Staphylococci and staphylococcal pathogenesis

Author: David Heinrichs
Publisher: Frontiers E-books
ISBN: 9782889190577
Release Date:
Genre:

Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.

Molecular Genetics of Mycobacteria

Author: Graham F. Hatfull
Publisher: American Society for Microbiology Press
ISBN: 9781555818838
Release Date: 2014-09-10
Genre: Science

A comprehensive collection of perspectives by experts in mycobacterial molecular biology Mycobacterium tuberculosis causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. Tuberculosis was named a global health emergency by the World Health Organization, a distinction no other disease has received. Although the study of mycobacterial genetics has expanded dramatically, with new investigations into mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 remain today. Advances in our understanding of mycobacterial genetics have been reflected in exciting recent developments. New diagnostic approaches can identify drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge. Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition, • Discusses key areas of current research in mycobacterial genetics • Explains the genetics of the physiology, metabolism, and drug sensitivities of M. tuberculosis • Presents genetic approaches for manipulating M. tuberculosis This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.