Staphylococcus

Author: Jodi A. Lindsay
Publisher: Horizon Scientific Press
ISBN: 9781904455295
Release Date: 2008
Genre: Science

Focusing on the staphylococcal genetics, this title brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the-art overview of the field.

Molecular Typing in Bacterial Infections

Author: Ivano de Filippis
Publisher: Springer Science & Business Media
ISBN: 9781627031851
Release Date: 2012-11-07
Genre: Science

Molecular Typing in Bacterial Infections covers common bacterial pathogenic agents, with the most effective methods for their identification and classification in the light of their specific epidemiology. The book will be a valuable resource for molecular typing of infectious diseases agents encountered in both the research and hospital clinical lab settings, as well as culture collections. Each chapter provides an overview of molecular approaches to typing bacterial pathogens. Part I gives a general overview of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology. In Part II, the relative strengths and weaknesses of the different methods applicable to the specific agents of infectious diseases are emphasized. Specific emphasis is placed on recent changes and updates in molecular typing.

Food Borne Pathogens and Antibiotic Resistance

Author: Om V. Singh
Publisher: John Wiley & Sons
ISBN: 9781119139157
Release Date: 2017-01-30
Genre: Medical

Food is an essential means for humans and other animals to acquire the necessary elements needed for survival. However, it is also a transport vehicle for foodborne pathogens, which can pose great threats to human health. Use of antibiotics has been enhanced in the human health system; however, selective pressure among bacteria allows the development for antibiotic resistance. Foodborne Pathogens and Antibiotic Resistance bridges technological gaps, focusing on critical aspects of foodborne pathogen detection and mechanisms regulating antibiotic resistance that are relevant to human health and foodborne illnesses This groundbreaking guide: • Introduces the microbial presence on variety of food items for human and animal consumption. • Provides the detection strategies to screen and identify the variety of food pathogens in addition to reviews the literature. • Provides microbial molecular mechanism of food spoilage along with molecular mechanism of microorganisms acquiring antibiotic resistance in food. • Discusses systems biology of food borne pathogens in terms of detection and food spoilage. • Discusses FDA’s regulations and Hazard Analysis and Critical Control Point (HACCP) towards challenges and possibilities of developing global food safety. Foodborne Pathogens and Antibiotic Resistance is an immensely useful resource for graduate students and researchers in the food science, food microbiology, microbiology, and industrial biotechnology. About the Editor Om V. Singh, PhD, is an Associate Professor of Microbiology at the University of Pittsburgh, Bradford in Bradford, PA, USA.

Staphylococcus

Author: Greg A. Somerville
Publisher: Caister Academic Press
ISBN: 9781910190500
Release Date: 2016-10-15
Genre: Medical

In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research. This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus aureus Infection and Disease

Author: Allen Honeyman
Publisher: Springer Science & Business Media
ISBN: 9780306468483
Release Date: 2006-04-11
Genre: Medical

Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agents and Pathogenesis series, presents chapters by the major researchers in the field.

Rapid Detection and Characterization of Foodborne Pathogens by Molecular Techniques

Author: Robert E. Levin
Publisher: CRC Press
ISBN: 142009243X
Release Date: 2009-10-26
Genre: Technology & Engineering

Decades of development of the polymerase chain reaction (PCR) have yielded a significant array of associated techniques that make it possible to rapidly detect low numbers of all known pathogenic microorganisms without the traditional, more taxing methods of cultivation and phenotypic characterization. Written by one of the most prolific and respected researchers in food safety, Rapid Detection and Characterization of Foodborne Pathogens by Molecular Techniques describes the application of molecular techniques for the detection and discrimination of major infectious bacteria associated with foods. The book puts a particular focus on genes associated with pathogenicity used in PCR, including real-time PCR for specific detection of pathogenic bacteria and the inherent limitations of such methodology with certain pathogens. It also emphasizes methods for extracting microorganisms from complex food matrices and DNA purification techniques. The coverage begins with a highly comprehensive review of real time PCR, complete with theoretical and operational concepts. Each chapter deals with a specific organism and the techniques applied to that organism. The text includes references on the use of PCR primers and DNA probes, the DNA sequence of each being listed at the end of each chapter to create a complete compendium. This is not a "recipe book", but rather a resource with sufficiently detailed information that allows readers to fully comprehend the methodology described and the significance of the results. Copiously illustrated with figures, tables, charts, and graphs, this is a detailed presentation of the major, contemporary studies involving the molecular detection, quantification, and subspecies differentiation of each organism. With objective assessments of the molecular techniques, their advantages, and limitations, the book allows investigators to readily identify the precise molecular technique and application most suitable for their research.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites

Author: Juan-Francisco Martín
Publisher: Springer
ISBN: 9781493911912
Release Date: 2014-09-09
Genre: Science

This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.

Diagnostic Pathology and Molecular Genetics of the Thyroid

Author: Yuri E. Nikiforov
Publisher: Lippincott Williams & Wilkins
ISBN: 9781451114553
Release Date: 2012-04-20
Genre: Medical

Diagnostic Pathology and Molecular Genetics of the Thyroid, Second Edition, offers a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, including neoplastic and non-neoplastic conditions. The book provides a detailed description of the surgical pathology of thyroid diseases side by side with major advances in immunohistochemistry and molecular genetics that can be used in evaluating thyroid tumors and non-neoplastic diseases.

Bacterial Pathogenesis

Author: Frank R. DeLeo
Publisher: Springer Science & Business Media
ISBN: 9781588297402
Release Date: 2008-01-31
Genre: Medical

Bacterial infections affect world health today as a leading cause of morbidity and mortality. This book presents in-depth methods and state-of-the-art protocols for investigating specific mechanisms of pathogenesis for a wide range of bacteria. Written by experts in the field, this invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections.

Molecular Techniques for the Study of Hospital Acquired Infection

Author: Steven L. Foley
Publisher: John Wiley & Sons
ISBN: 111806383X
Release Date: 2011-08-04
Genre: Medical

Providing a broad overview of the microbial pathogens associated with hospital-acquired human illness, Techniques for the Study of Hospital Acquired Infection examines the cost-effective use of laboratory techniques in nosocomial infectious disease epidemiology and control. This concise guide addresses the cost benefits of combining modern molecular techniques with the traditional activities of infection control departments. The book is useful as a guide to hospital infection control programs as well as a text for medical practitioners, grad/medical students, researcher scientists, population biologists, molecular biologists, and microbiologists.

Molecular Genetics of Bacteria

Author: Larry Snyder
Publisher: Amer Society for Microbiology
ISBN: 155581204X
Release Date: 2003
Genre: Science

This advanced level textbook offers an in-depth look at molecular biology and biochemistry. The breadth and diversity of bacterial genetics are explored in discussions of microbial systems beyond the much-studied E Coli.