The Art of Writing Reasonable Organic Reaction Mechanisms

Author: Robert B. Grossman
Publisher: Springer Science & Business Media
ISBN: 9780387954684
Release Date: 2007-07-31
Genre: Science

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

The Art of Writing Reasonable Organic Reaction Mechanisms

Author: Robert B. Grossman
Publisher: Springer Science & Business Media
ISBN: 9780387215457
Release Date: 2006-04-18
Genre: Science

Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

The Art of Writing Reasonable Organic Reaction Mechanisms

Author: Robert Grossman
Publisher: Springer
ISBN: UCSD:31822030026090
Release Date: 1999
Genre: Science

This book shows readers how to draw reasonable mechanisms for reactions they have never seen before. This skill will help readers develop a good command of electron-pushing before tackling the detailed mechanistic analysis of physical organic chemistry. It is organized according to mechanistic types in order to clarify the basic mechanistic similarities among apparently diverse reactions. One of the unique features of this book is the common error alert, which warns about common pitfalls and misconceptions.

Organic Reaction Mechanisms

Author: Mar Gomez-Gallego
Publisher: Springer Science & Business Media
ISBN: 9783642187889
Release Date: 2012-12-06
Genre: Science

Organic Reaction Mechanisms shows readers how to interpret the experimental data obtained from an organic reaction, and specifically how an organic reaction mechanism can be considered or rejected based on the analysis of the experimental evidence. Whilst examining a series of selected examples of mechanisms, the text focuses on real cases and discusses them in detail. The examples are arranged to elucidate key aspects of organic reaction mechanisms. The authors employ all the types of information that the authors of the original work considered useful and necessary, including spectroscopic data, kinetic and thermodynamic data, isotopic labelling and organic reactivity. The book makes an excellent primer for advanced undergraduates in chemistry who are preparing for exams and is also useful for graduate students and instructors.

Writing Reaction Mechanisms in Organic Chemistry

Author: Audrey Miller
Publisher: Academic Press
ISBN: 0124967124
Release Date: 2000
Genre: Science

Writing Reaction Mechanisms in Organic Chemistry, Second Edition, is an invaluable guide to charting the movements of atoms and electrons in the reactions of organic molecules. Miller and Solomon illustrate that understanding organic reactions is based on applying general principles rather than the rote memorization of unrelated processes, and, in turn, emphasize that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. Students and research chemists alike will find this book useful in providing a method of organizing and synthesizing an oftentimes overwhelming quantity of information into a set of general principles and guidelines for determining and describing organic reaction mechanisms. * Essential for those students who need to have mechanisms explained in greater detail than most organic chemistry textbooks provide. * Illustrated with hundreds of chemical structures * Extensively rewritten and reorganized to make the presentation and format even easier for students to use * Contains many problem sets and answers to all problems to help students work through general principles and applications * Appendixes have been added to this edition that contain easily referenced information on Lewis structures, symbols for chemical notation, and the relative acidities of common substances

A Handbook of Organic Chemistry Mechanisms

Author: Peter Wepplo
Publisher: Curved Arrow Press
ISBN: 9780977931330
Release Date: 2009-02-01
Genre: Science

A Handbook to Organic Chemistry Mechanisms is designed to accompany a standard organic chemistry textbook. The book presents complete mechanisms, start to finish, without any steps skipped or left out. The mechanisms have been carefully written to show each step in a logical and easy to follow format. Students have enthusiastically attested to the ease with which they could understand the mechanisms. Reaction mechanisms are one of the most challenging aspects of organic chemistry. This book is derived from Part D of A Guide to Organic Chemistry Mechanisms. That book is a guided inquiry workbook that shows students how to study and enables them to learn reaction mechanisms. Student knowledge is increased step by step by completing mechanisms at easy, moderate, and textbook levels of difficulty. A Handbook to Organic Chemistry Mechanisms also relies on example-based teaching. Chemical reactions can be learned in context, the way infants learn. Learning reactions from rules is difficult when there are many exceptions. Substitution and elimination reactions are noteworthy due to the number of conditions that must be accounted for. With example-based teaching, you can deduce the importance that stereochemistry, structure, solvent, leaving group, charge, basicity, or nucleophilicity may have on a reaction. A Handbook to Organic Chemistry Mechanisms has been designed with the principle that our brains are pattern-matching machines. Therefore, an emphasis has been placed upon the patterns of reactions. Each chapter represents a basic mechanistic theme. That theme is repeated with the examples. Insightful explanations have been included with the mechanisms. This book will be a valuable resourcefor reviewing for an exam, solving problems, or studying for the MCAT.

Strategic Applications of Named Reactions in Organic Synthesis

Author: Laszlo Kurti
Publisher: Elsevier
ISBN: 9780080575414
Release Date: 2005-04-29
Genre: Science

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings

Reaction Mechanisms At a Glance

Author: Mark G. Moloney
Publisher: Wiley-Blackwell
ISBN: 0632050020
Release Date: 1999-12-03
Genre: Science

Students at all levels find considerable difficulty in applying their knowledge of organic chemistry to the solution of problems, often relying on memory alone. This book takes a unique approach to show that a general problem-solving strategy is applicable to many of the common reactions. Using a novel 'at-a-glance' layout, the left-hand page provides a stepwise procedure for working through the reaction mechanisms, with helpful hints about the underlying chemistry, and the facing page contains a fully worked-through answer.

Organic Chemistry

Author: Robert V. Hoffman
Publisher: John Wiley & Sons
ISBN: 9780471648727
Release Date: 2004-11-26
Genre: Science

Ideal for those who have previously studies organic chemistry but not in great depth and with little exposure to organic chemistry in a formal sense. This text aims to bridge the gap between introductory-level instruction and more advanced graduate-level texts, reviewing the basics as well as presenting the more advanced ideas that are currently of importance in organic chemistry. * Provides students with the organic chemistry background required to succeed in advanced courses. * Practice problems included at the end of each chapter.

Introduction to Strategies for Organic Synthesis

Author: Laurie S. Starkey
Publisher: John Wiley & Sons
ISBN: 9781119347231
Release Date: 2018-03-23
Genre: Science

Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule. Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule. This new Second Edition of Introduction to Strategies for Organic Synthesis: Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions Helps students envision forward reactions and backwards disconnections as a matter of routine Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions Provides clear explanations in easy-to-follow, student-friendly language Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.

Advanced organic chemistry

Author: Jerry March
Publisher: John Wiley & Sons
ISBN: UOM:39015050421331
Release Date: 1992
Genre: Science

After four editions, it2s still the reference students and professionals count on. Advanced Organic Chemistry Fourth Edition Only one reference has brought consistently incisive, up-to date, and comprehensive coverage of the most useful reactions in organic chemistry directly to the fingertips of both students and professionals: Advanced Organic Chemistry. Organized by reaction type, a feature that makes clear the basic principles underlying the nearly 580 reactions described, Advanced Organic Chemistry offers instant access to each reaction2s scope, limitations, and mechanisms. Balancing timely detail and informative breadth, this new updated Fourth Edition: Describes the structure of organic compounds, including chemical bonding and stereochemistry Reviews general reaction mechanisms, including ordinary reactions and photochemical reactions Includes a survey of reactions, arranged by reaction type and by which bonds are broken and formed Includes IUPAC2s newest system for designating reaction mechanisms Features an index to the methods used for preparing given types of compounds Contains more than 15,000 references-5,000 new to this edition-to original papers

Advanced Organic Chemistry

Author: Francis A. Carey
Publisher: Springer Science & Business Media
ISBN: 9780306468568
Release Date: 2006-05-02
Genre: Science

Since its original appearance in 1977, Advanced Organic Chemistry has found wide use as a text providing broad coverage of the structure, reactivity and synthesis of organic compounds. The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types, including nucleophilic substitution, addition reactions, carbonyl chemistry, aromatic substitution and free radical reactions. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed. The Fourth Edition updates certain topics that have advanced rapidly in the decade since the Third Edition was published, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis. The two parts stand alone, although there is considerable cross-referencing. Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism. Part B emphasizes the most general and useful synthetic reactions. The focus is on the core of organic chemistry, but the information provided forms the foundation for future study and research in medicinal and pharmaceutical chemistry, biological chemistry and physical properties of organic compounds. The New Revised 5th Edition will be available shortly. For details, click on the link in the right-hand column.

Organic Mechanisms

Author: Reinhard Bruckner
Publisher: Springer Science & Business Media
ISBN: 9783642036514
Release Date: 2010-04-30
Genre: Science

“Much of life can be understood in rational terms if expressed in the language of chemistry. It is an international language, a language without dialects, a language for all time, a language that explains where we came from, what we are, and where the physical world will allow us to go. Chemical Language has great esthetic beauty and links the physical sciences to the b- logical sciences. ” from The Two Cultures: Chemistry and Biology by Arthur Kornberg (Nobel Prize in Physiology and Medicine, 1959) Over the past two centuries, chemistry has evolved from a relatively pure disciplinary pursuit to a position of central importance in the physical and life sciences. More generally, it has p- vided the language and methodology that has unified, integrated and, indeed, molecularized the sciences, shaping our understanding of the molecular world and in so doing the direction, development and destiny of scientific research. The “language of chemistry” referred to by my former Stanford colleague is made up of atoms and bonds and their interactions. It is a s- tem of knowledge that allows us to understand structure and events at a molecular level and increasingly to use that understanding to create new knowledge and beneficial change. The words on this page, for example, are detected by the eye in a series of events, now generally understood at the molecular level.

Organic Reaction Mechanisms

Author: William C. Groutas
Publisher: Wiley
ISBN: 0471282510
Release Date: 1999-09-16
Genre: Science

This hands-on manual allows readers to gain a better understanding of organic reaction mechanisms by solving a wide range of problems. Answers for the problems are included along with mini-reviews that summarize and emphasize fundamental principles. This approach sharpens readers' reasoning ability and critical thinking.