Großartig, fesselnd und folgenreich: Pulitzer-Preisträger Siddhartha Mukherjee erzählt meisterhaft die Geschichte der Entzifferung des Mastercodes, der unser Menschsein bestimmt. Als Siddhartha Mukherjee seinen Bestseller ›Der König aller Krankheiten‹ beendet hatte, machte er sich auf eine Reise in die indische Heimat. Er besucht Cousin Moni, der an Schizophrenie leidet – wie auffällig viele seiner Verwandten. Fasziniert beginnt Mukherjee sich mit der Geschichte der Gene zu beschäftigen: Von den Erbsenkreuzungen Mendels bis zur neuesten Gen-Bearbeitungs-Methode CRISPR schreibt Mukherjee den spannenden Roman einer wissenschaftlichen Suche und verwebt ihn mit der Geschichte seiner Familie. Das große Buch eines begnadeten Erzählers und Arztes, das gewaltige Panorama einer machtvollen Entdeckung, die man nun endlich versteht. Packend und einzigartig. »Wer wissen will, was es bedeutet, Mensch zu sein, sollte dieses Buch lesen.« Boston Globe »Lesen Sie dieses Buch, so werden Sie auf die Zukunft bestens vorbereitet sein. « Sunday Times »Meisterhaft aufgebaut, wunderbar erzählt [...] Mukherjee ist ein Genie darin, zutiefst menschliche Geschichten hinter abstrakten Ideen zu entdecken.« Andrew Solomon, Washington Post »Eine inspirierende und ungemein bewegende Lektüre.« San Francisco Chronicle
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
Release Date: 2016-05-17
THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
A history of the science of genetics discusses its roots in heredity, the discovery of DNA, the Human Genome Project, the applications of genetic work, and the controversy surrounding genetic engineering.
p”Ein auch heute noch bedeutsamer Klassiker“ Daily Express Sind wir Marionetten unserer Gene? Nach Richard Dawkins ́ vor über 30 Jahren entworfener und heute noch immer provozierender These steuern und dirigieren unsere von Generation zu Generation weitergegebenen Gene uns, um sich selbst zu erhalten. Alle biologischen Organismen dienen somit vor allem dem Überleben und der Unsterblichkeit der Erbanlagen und sind letztlich nur die "Einweg-Behälter" der "egoistischen" Gene. Sind wir Menschen also unserem Gen-Schicksal hilflos ausgeliefert? Dawkins bestreitet dies und macht uns Hoffnung: Seiner Meinung nach sind wir nämlich die einzige Spezies mit der Chance, gegen ihr genetisches Schicksal anzukämpfen.
Author: Worth Books
Publisher: Open Road Media
Release Date: 2016-12-13
Genre: Study Aids
So much to read, so little time? This brief overview of The Gene tells you what you need to know—before or after you read Siddhartha Mukherjee’s book. Crafted and edited with care, Worth Books set the standard for quality and give you the tools you need to be a well-informed reader. This short summary and analysis of The Gene by Siddhartha Mukherjee includes: Historical context Chapter-by-chapter summaries Detailed timeline of key events Important quotes Fascinating trivia Glossary of terms Supporting material to enhance your understanding of the original work About Siddhartha Mukherjee’s The Gene: From the Pulitzer Prize–winning author of The Emperor of All Maladies, The Gene is a rigorously scientific, broadly historical, and candidly personal account of the development of the science of genetics, the dramatic ways genes can affect us, and the enormous moral questions posed by our ability to manipulate them. As Siddhartha Mukherjee maps out the fascinating biography of the gene, from research and experimentation to scientific breakthroughs, he always returns to the narrative of his own family’s tragic history of mental illness, reminding us that despite our huge leaps in knowledge, there is still much we do not understand about the incredibly complex human genome. The Gene is an important read for anyone concerned about a future that may redefine what it means to be human. The summary and analysis in this ebook are intended to complement your reading experience and bring you closer to a great work of nonfiction.
The Gene by Siddhartha Mukherjee | Summary & Analysis Preview: The Gene by Siddhartha Mukherjee describes the history of genetic research, the impact of genetic inheritance on his family, and the potential for future applications of gene science. Mukherjee’s father and uncles struggled with disorders such as schizophrenia and bipolar disorder, both of which are linked to genetic mutations. After centuries of conjecture about the nature of familial inheritance, naturalist Charles Darwin published his theory of evolution in 1859. In 1865, botanist Gregor Mendel proposed that genetic information is passed down from both the paternal and maternal sides of the family in the form of paired genes. Thereafter, eugenics gradually became socially accepted and programs to sterilize the disabled and deviant were established in the United States. The practice of eugenics became socially abhorrent following World War II and the revelations of genocidal practices in Nazi Germany and Stalinist Russia. Between 1908 and 1963, scientists continued studying genetic material… PLEASE NOTE: This is key takeaways and analysis of the book and NOT the original book. Inside this Instaread Summary of The Gene · Overview of the Book · Important People · Key Takeaways · Analysis of Key Takeaways The Gene by Siddhartha Mukherjee | Summary & Analysis Preview: The Gene by Siddhartha Mukherjee describes the history of genetic research, the impact of genetic inheritance on his family, and the potential for future applications of gene science. Mukherjee’s father and uncles struggled with disorders such as schizophrenia and bipolar disorder, both of which are linked to genetic mutations. After centuries of conjecture about the nature of familial inheritance, naturalist Charles Darwin published his theory of evolution in 1859. In 1865, botanist Gregor Mendel proposed that genetic information is passed down from both the paternal and maternal sides of the family in the form of paired genes. Thereafter, eugenics gradually became socially accepted and programs to sterilize the disabled and deviant were established in the United States. The practice of eugenics became socially abhorrent following World War II and the revelations of genocidal practices in Nazi Germany and Stalinist Russia. Between 1908 and 1963, scientists continued studying genetic material… PLEASE NOTE: This is key takeaways and analysis of the book and NOT the original book. Inside this Instaread Summary of The Gene: · Overview of the Book · Important People · Key Takeaways · Analysis of Key Takeaways About the Author With Instaread, you can get the key takeaways, summary and analysis of a book in 15 minutes. We read every chapter, identify the key takeaways and analyze them for your convenience.
Author: Jay Joseph
Publisher: Algora Publishing
Release Date: 2004
Jay Joseph's timely, challenging book provides a much-needed rebuttal of the evidence cited in support of genetic theories in psychiatry and psychology, which are based mainly on twin and adoption studies. He shows that, far from establishing the importance of genes, psychiatric genetic and behavior genetic research on twins and adoptees has been plagued by researcher bias, unsound methodology, and a reliance on erroneous theoretical assumptions. Furthermore, he discusses how this faulty research has been used to support the interests of those attempting to bolster conservative social and political agendas. Under the Microscope Dr. Jay Joseph provocatively challenges current genetic theories and the evidence cited to support them - in particular, genes' alleged role in criminal behavior, IQ, heritability and molecular genetic research - and maintains they are all part of the "Gene Illusion."
Author: Evelyn Fox KELLER
Publisher: Harvard University Press
Release Date: 2009-06-30
In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology's progress from gene to genome in one hundred years, "The Century of the Gene" also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene--word and object--as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.
Author: Bonnie Rochman
Publisher: Scientific American / Farrar, Straus and Giroux
Release Date: 2017-02-28
Genre: Family & Relationships
A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.
Author: Celeste Michelle Condit
Publisher: Univ of Wisconsin Press
Release Date: 1999
The Meanings of the Gene is a compelling look at societal hopes and fears about genetics in the course of the twentieth century. The work of scientists and doctors in advancing genetic research and its applications has been accompanied by plenty of discussion in the popular press—from Good Housekeeping and Forbes to Ms. and the Congressional Record—about such topics as eugenics, sterilization, DNA, genetic counseling, and sex selection. By demonstrating the role of rhetoric and ideology in public discussions about genetics, Condit raises the controversial question, Who shapes decisions about genetic research and its consequences for humans—scientists, or the public? Analyzing hundreds of stories from American magazines—and, later, television news—from the 1910s to the 1990s, Condit identifies three central and enduring public worries about genetics: that genes are deterministic arbiters of human fate; that genetics research can be used for discriminatory ends; and that advances in genetics encourage perfectionistic thinking about our children. Other key public concerns that Condit highlights are the complexity of genetic decision-making and potential for invasion of privacy; conflict over the human genetic code and experimentation with DNA; and family genetics and reproductive decisions. Her analysis reveals a persistent debate in the popular media between themes of genetic determinism (such as eugenics) and more egalitarian views that place genes within the complexity of biological and social life. The Meanings of the Gene offers an insightful view of our continuing efforts to grapple with our biological natures and to define what it means, and will mean in the future, to be human.
Author: James Schwartz
Publisher: Harvard University Press
Release Date: 2009-06-30
Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. This book offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.
Author: James D. Watson
Publisher: Benjamin-Cummings Publishing Company
Release Date: 2014
Now completely up-to-date with the latest research advances, the Seventh Edition retains the distinctive character of earlier editions. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.
Author: Frederic Lawrence Holmes
Publisher: Yale University Press
Release Date: 2008-10-01
This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer’s accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer’s remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer’s creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.