Author: Cedric A. Mims
Publisher: Gulf Professional Publishing
Release Date: 2001
Infectious diseases are the leading cause of death worldwide, and are increasing in almost every nation, including the United States; they ranked third among the leading causes of death in the U.S. in 1992. Infectious diseases can be caused by bacteria, parasites, viruses, and other microbes such as fungus. They are part of everyday life, and range in severity from strep throat to AIDS. Mims' Pathogenesis of Infectious Disease has been the landmark book in the field. This revised edition provides an up-to-date picture of the global burden of infectious disease. It explains principles clearly and completely, using examples from various infections. It covers the mechanisms for spread of disease, immune response, and recovery, and is ideal as a course text for graduate and undergraduate students. New features include: * Microbial gene sequencing * Role of bacterial virulence factors in vivo * Latest data on tuberculosis - the number one infectious disease worldwide * Role of pathogenic cytokines * Significance of toxins * An update on vaccines, prions, immune evasion, microbial ligands and receptors
Author: Abul K. Abbas
Publisher: Elsevier Health Sciences
Release Date: 2011-04-15
Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subject of immunology. Recognize the clinical relevance of the immunology through discussions of the implications of immunologic science for the management of human disease. Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art. Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.
Author: Katherine Snyder
Publisher: Elsevier Health Sciences
Release Date: 2014-04-14
Written specifically to meet the needs of surgical technologists, Pharmacology for the Surgical Technologist, 3rd Edition focuses on the uses of medicines, agents, and solutions in surgery. An introduction to pharmacology covers basic math skills, pharmacologic principles, and drug administration, and is followed by detailed descriptions of common surgical medications along with anesthesia in surgical and emergency situations. This edition adds a new index of drugs by surgical specialty, and a companion Evolve website reinforces your understanding with practical activities and exercises, drug calculations, and more. In this book, Surgical Technology educators Katherine C. Snyder and Chris Keegan cover all areas of pharmacology that are designated in the core curriculum by the AST (Association of Surgical Technology). Coverage of pharmacology includes all areas designated in the core curriculum by the Association of Surgical Technology (AST). A review of basic math skills and pharmacologic principles makes it easier to apply the information to surgical situations. Learning tools in each chapter include learning objectives, key terms with definitions, chapter summaries, and review questions. Important and practical advice is provided with Caution alerts, Tech Tips, Notes, and First Assist boxes. Common surgical medications are covered by category and include descriptions of surgical applications. The free companion Evolve website includes a NEW online study guide with chapter objectives, outlines, key term activities, drug calculations, chapter exercises and review questions, critical thinking exercises, and chapter quizzes. Expanded appendix includes an index of Drugs by Surgical Specialty focusing on specific uses of medicines and solutions in surgery. Revised Anesthesia unit helps you assist the anesthesia care team with updated protocols and a more cohesive organization for preoperative medications, patient monitoring and local and regional anesthesia, general anesthesia, and emergency situations. References in each chapter make it easier to find source material.
This section provides just a few highlights of new content and organizational improvements in BIOLOGY, Eighth Edition. UNIT ONE The Chemistry of Life New examples make basic chemistry more engaging for students, including an explanation of why steam can burn your skin in Chapter 3, the structures of the enantiomeric medications ibuprofen and albuterol in Chapter 4, and information on trans fats in Chapter 5. Anew Inquiry Figure in Chapter 3 relates acidity to the emerging global problem of ocean acidification and its effects on coral reefs. The new Inquiry Figure in Chapter 5 shows Roger Kornberg's 3-D model of the RNA polymerase-DNA-RNA complex, work for which he won the 2006 Nobel Prize in Chemistry. UNIT TWO The Cell The judicious addition of recent research includes updated coverage of the sensory roles ofprimary cilia in Chapter 6, new developments regarding the membrane model in Chapter 7, and Paul Nurse's Nobel Prize-winning work on the cell cycle in Chapter 12. Chapter 11 now ends with a section on apoptosis, formerly in Chapter 21. New Inquiry Figures in this unit describe research on the role of microtubules in orienting cellulose in cell walls (Chapter 6), allosteric regulators of enzymes (Chapter 8), ATP synthase (Chapter 9), yeast cell signaling (Chapter ll), and a cell cycle regulator (Chapter 12). UNIT THREE Genetics Chapter 14 now includes "Tips for Genetics In Chapter 15, sex linkage is discussed directly after the discussion of the white-eye trait in Morgan's fruit flies. Chapter 16 covers replication of the bacterial chromosome and the structure of the eukaryotic chromosome (including a new Exploring Figure), formerly in Chapters 18 and 19, respectively. We have reorganized Chapters 18-21 with the dual aims of telling a more coherent story and facilitating instructors' coverage of molecular genetics. Regulation of gene expression for both bacteria and eukaryotes is now consolidated in Chapter 18, which also includes a concept section on the crucial role of small RNAs in eukaryotes. We have streamlined material on the genetic basis of development (formerly in Chapter 21), and included it in Chapter 18, where it provides the ultimate example of gene regulation. Chapter 18 ends with a section on the molecular basis of cancer (previously in Chapter 19), to demonstrate what happens when gene regulation goes awry. Material on bacterial genetics in Seventh Edition Chapter 18 has been moved to other chapters within the genetics unit and to Chapter 27 on prokaryotes. Chapter 19 now covers only viruses (from Seventh Edition Chapter 18), giving this chapter the flexibility to be assigned at any point in the course. Chapter 20 continues to cover biotechnology, but genome sequencing and analysis have been moved to Chapter 21. Cloning and stem cell production are now in Chapter 20. Newly explained techniques include the screening of an arrayed library, BAC clones, Northern blotting, RT-PCR, and in situ hybridization. The explosion of discoveries about genomes and their evolution led us to develop a chapter devoted to this subject, the new Chapter 21. This chapter consolidates new material with topics from Chapters 19-21 of the Seventh Edition. UNIT FOUR Mechanisms of Evolution Our revision emphasizes the centrality of evolution to biology and the breadth and depth of evidence for evolution. New examples and Inquiry Figures present data from field and laboratory studies and reveal how scientists study evolution. Chapter 22 discusses how evolution can be viewed as both a pattern and a process, and introduces three key observations about life that are explained by evolution: the match between organisms and their environments (adaptation); the shared characteristics (unity) oflife; and the diversity of life. This discussion serves as a conceptual anchor throughout Units Four and Five. Chapters 24 and 25 have been significantly reorganized. Chapter 24 is now more tightly focused on speciation, enabling better pacing of this highly conceptual material. A new concept section explores hybrid zones as naturallaboratories for studying speciation. Chapter 25 focuses on macroevolution, incorporating topics formerly in Chapters 24 and 26, such as the correlations between Earth's geologic and biological history. But the primary storyline concerns what we can learn from the fossil record about the evolutionary history of life. New text and figures explore how the rise and fall of dominant groups of organisms are linked to large-scale processes such as continental drift, mass extinctions, and adaptive radiations. Coverage of evo-devo has been expanded. Phylogenetic trees are introduced earlier, in a new section on "tree-thinking" in Chapter 22. This material supports students in interpreting diagrams before studying phylogenetics more fully in Chapter 26. UNIT FIVE The Evolutionary History of Biological Diversity A new Chapter 26, Phylogeny and the Tree of Life, introduces the unit. Extending material formerly in Chapter 25, it describes how evolutionary trees are constructed and underscores their role as tools for understanding relationships, rather than facts to be memorized. New sections address common misconceptions in interpreting trees and help motivate students with practical applications. Chapter 27 has a new concept section on prokaryotic reproduction, mutation, and recombination (formerly in Chapter 18). This unifies the coverage of prokaryote biology and supports students in developing a fuller understanding of these microorganisms. Throughout Unit Five, along with updating the phyloge· nies of various groups of organisms-introducing, for exam· pie, the hypothesis of eukaryotic phylogeny (in Chapter 28) -we have found new opportunities to use the study of phylogeny as an opportunity to illustrate the iterative nature of the scientific process. We aim to help students stay focused on the big picture ofwhy biologists study evolutionary relationships. Each chapter also now includes an Inquiry figure that models how researchers study organisms and their relationships. At the same time, in each chapter we highlight the key roles that various organisms play in the biosphere as well as their applied importance for humans. UNIT SIX Plant Form and Function Revisions to this unit draw more attention to the experimental basis of our understanding of plant biology. New examples include recent progress toward identifying the flowering "hormone" (Chapter 39). Featured in new Inquiry Figures are experiments demonstrating, for example, that trichomes affect insect feeding (Chapter 35) and that informational molecules transported through the symplast affect plant de· velopment (Chapter 36). In Chapter 36, now titled Resource Acquisition and Transport in Vascular Plants, a new first concept section explores how architectural features of plants facilitate resource acquisition, helping students relate the transport of water and nutrients to what they learned in Chapter 35 about plant structure and growth. Another new concept section, on symplastic transport, discusses recent insights into changes in plasmodesmata shape and number and the transmission of electrical and molecular signals throughout the plant. This unit now has more examples of practical applica· tions of plant biotechnology. For instance, Chapter 37 dis· cusses how genetic modification has increased the resist· ance of some plants to aluminum toxicity and has improved the flood tolerance of rice crops. Chapter 38 elaborates on the principles of plant breeding and incorporates a new section on genetic engineering of biofuels. x New to the Eighth Edition UNIT SEVEN Animal Form and Function An evolutionary perspective more strongly pervades this unit, underscoring how environment and physical laws shape adaptations across animal groups. Each chapter now includes at least one Inquiry Figure; together, these figures highlight the wide range of methodologies used to study animal physiology, including several experiments using molecular biology techniques students studied earlier in the book. Chapter 40 has been revised and reorganized to highlight functional relationships at all levels of organization in animal bodies; thermoregulation serves as an extended example throughout the chapter. Chapter 43, The Immune System, has been extensively revised. For instance, we now contrast recognition of pathogen class in innate immunity with antigenspecific recognition in adaptive immunity, helping overcome the common misconception that recognition is absent in innate immunity. We have divided the former nervous system chapter into m'o, enabling us to better pace difficult material and high· light dynamic current research by focusing first on cellular processes in Chapter 48, and then on nervous system or· ganization and function in Chapter 49. Chapter 50 rounds out the discussion of nervous system function by examining sensory and motor mechanisms. This sequence leads naturally into Chapter 51 on animal behavior (formerly in Unit Eight), which ties together aspects of genetics, natural selection, and physiology, and provides a bridge to the ecology unit. UNIT EIGHT Ecology This unit, which now includes Chapters 52·56, incorporates many new examples that demonstrate a range of methods and scales ofstudy. For example, a new figure in Chapter 52 describes a large·scale field experiment in which researchers manipulated precipitation levels in forest plots, while new Research Method figures describe determining population size using the mark-recapture method (Chapter 53), using molecular tools to measure diversity of soil microorganisms (Chapter 54), and determining primary production with satellite data (Chapter 55). By building on earlier units, we hope to demonstrate how ecology represents a fitting capstone to the book. We provide more microbial examples and more aquatic ones, from diverse locations around the globe. For instance, Chapter 52 now discusses the importance of salinity in determining the distribution ofaquatic organisms, and Chapter 54's coverage of the intermediate disturbance hypothesis includes a new figure on a quantitative test of the hypothesis in New Zealand streams. The unit highlights the great relevance of ecology to society and to students' lives. A new concept section in Chapter 54, for example, discusses how community ecology helps us understand pathogen life cycles and control disease. BIOLOGY Eighth Edition Neil A. Campbell Jane B. Reece Berkeley, California Lisa A. Urry Mills College. Oakland, California Michael L. Cain Bowdoin College, Brunswick, Maine Steven A. Wasserman University of California, San Diego Peter V. Minorsky Mercy College, Dobbs Ferry, New York Robert B. Jackson Duke University, Durham, North Carolina PEARSON -- BeI\.iamin Cummings San Francisco Boston New York Cape Town Hong Kong London Madrid Mexico City Montreal Munich Paris Singapore Sydney Tokyo Toronto
Author: Abul K. Abbas
Publisher: Elsevier Health Sciences
Release Date: 2010-01-26
This updated 3rd edition of Basic Immunology provides a readable and concise introduction to the workings of the human immune system, with emphasis on clinical relevance. The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. You’ll get the latest coverage on regulatory T cells, biology of the Th17 subset of CD4+ T cells, and more. The full-color artwork, comprehensive glossary, and clinical cases are just some of the features that reinforce and test your understanding of how the immune system functions. Covers the most up-to-date immunology information including regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Provides a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Presents beautiful full-color artwork for enhanced visual learning.
Author: Clare Stephenson
Publisher: Elsevier Health Sciences
Release Date: 2011-07-26
The Complementary Therapist's Guide to Conventional Medicine is a unique textbook for students and practitioners of complementary medicine, offering a systematic comparative approach to Western and Eastern medicine. Practitioners of complementary medicine increasingly find themselves working alongside conventionally trained doctors and nurses and it is vital for them to develop a core understanding of conventional medical language and philosophy. The book is designed as a guide to understanding conventional medical diagnoses, symptoms and treatments, whilst also encouraging the reader to reflect on and translate how these diagnoses may be interpreted from a more holistic medical perspective. Throughout the text the practitioner/student is encouraged to see that conventional and more holistic interpretations are not necessarily contradictory, but instead are simply two different approaches to interpreting the same truth, that truth being the patient's symptoms. After introductory sections on physiology, pathology and pharmacology, there follow sections devoted to each of the physiological systems of the body. In these, the physiology of each system is explored together with the medical investigation, symptoms and treatments of the important diseases which might affect that system. As each disease is described, the reader is encouraged to consider the corresponding Chinese medical perspective. The textbook concludes with chapters relating specifically to dealing with patients in practice. In particular these focus on warning signs of serious disease, supporting patients on medication and ethical issues which may arise from management of patients which is shared with conventional practitioners. The book also offers a detailed summary of 'Red Flag symptoms' which are those which should be referred for 'Western' medical investigation or emergency medical treatment, and also a guide to how patients can be safely supported in withdrawing from conventional medication, when this is clinically appropriate. Those wishing to use the text for systematic study can make use of the question and problem-solving approach offered on the accompanying CD to which references to self study exercises appear at regular stages throughout the book. This means that the text can be easily adapted to form the basis of a study course in clinical medicine for students of complementary medicine. In addition to the self-testing questions and answers, the supporting CD also contains checklists for revision and full-colour illustrations. ABOUT THE AUTHOR Clare Stephenson is a qualified medical practitioner who worked in hospital medicine, general practice and public health medicine for a number of years before training in Traditional Chinese Medicine (TCM) and acupuncture. Over the course of a decade she developed and taught an undergraduate course for students of Chinese medicine on Western medicine and how it relates to TCM. She is particularly committed to encouraging communication and understanding between practitioners of different health disciplines. She currently works as a GP in Oxfordshire.
Author: Institute of Medicine
Publisher: National Academies Press
Release Date: 2003-03-26
The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.
Author: Anthony A. Nash
Publisher: Academic Press
Release Date: 2015-01-24
Mims' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery. Describes the origin and molecular biology of pandemic influenza, HIV1, and HIV2 as well as the recent work on papillomaviruses, herpesviruses, BSE, and variant CJD Contains the latest data on tuberculosis, microbial evasion of immune defenses, and the spread of antibiotic resistance genes among bacteria Provides an update on vaccines, prions, immune evasion, and microbial ligands and receptors Gives an up-to-date picture of the global burden of infectious diseases
Author: Peter Lydyard
Publisher: Taylor & Francis
Release Date: 2011-03-31
BIOS Instant Notes in Immunology, Third Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts-an ideal revision checklist-followed by a description of the subject that focuses on core information, with clear,
Author: Eric R. Taylor
Publisher: Nova Publishers
Release Date: 2001-01-01
Genre: Social Science
This is a non-technical narrative of chemical, biological warfare and terrorism (CBWT) for the general, non-scientist, non-military background reader. It examines the scientific and military basis and considerations behind the use of chemical and biological agents to injure and kill people. It explains in the simplest terms possible the various agent types, their use, effects on people, how they injure or kill, and the means of detection, treatment, antidotes and decontamination. Where technical terms are introduced, they are clearly and simply defined. The tactical considerations for the use of CBWT agents also is explained as it applies to terrorist use against civilian populations. The book also views the nature of the threat to civilians, self-defence and warning techniques, and measures one may take to protect family and self if living near a chemical plant. It is for education and where possible, self-defence and awareness. After all, the greatest weapons used by the terrorist is ignorance and fear.
Author: B.B. Biswas
Publisher: Springer Science & Business Media
Release Date: 1998-04-30
Recent years have seen tremendous progress in unraveling the molecular basis of different plant-microbe interactions. Knowledge has accumulated on the mecha nisms of the microbial infection of plants, which can lead to either disease or resistance. The mechanisms developed by plants to interact with microbes, whether viruses, bacteria, or fungi, involve events that can lead to symbiotic association or to disease or tumor formation. Cell death caused by pathogen infection has been of great interest for many years because of its association with plant resistance. There appear to be two types of plant cell death associated with pathogen infection, a rapid hypersensitive cell death localized at the site of infection during an incompatible interaction between a resistant plant and an avirulent pathogen, and a slow, normosensitive plant cell death that spreads beyond the site of infection during some compatible interactions involving a susceptible plant and a virulent, necrogenic pathogen. Plants possess a number of defense mechanisms against infection, such as (i) production of phytoalexin, (ii) formation of hydrolases, (iii) accumulation of hydroxyproline-rich glycoprotein and lignin deposition, (iv) production of pathogen-related proteins, (v) produc tion of oligosaccharides, jasmonic acid, and various other phenolic substances, and (vi) production of toxin-metabolizing enzymes. Based on these observations, insertion of a single suitable gene in a particular plant has yielded promising results in imparting resistance against specific infection or disease. It appears that a signal received after microbe infection triggers different signal transduction pathways.
Author: Subhash Chandra Parija
Publisher: Elsevier Health Sciences
Release Date: 2014-02-10
The second edition of the Textbook of Microbiology and Immunology provides a fully updated text on various aspects of microbiology and infectious diseases, which makes it the most authoritative and informative text in medical microbiology. It is a must have book for preparing MBBS examination as well as for preparing PG entrance test. Clear, succinct, and comprehensive information on various aspects of microbiology and immunology. Thoroughly revised information. Key Points highlighting the need to know aspects of the discussed topics. Tables and figures for better understanding. Case studies at the end of chapters for self-assessment. Special emphasis on emerging and re-emerging pathogens and antimicrobial resistance. Color photographs to aid in better understanding. Covers recent advances in molecular diagnosis and vaccines.
Author: Michel Tibayrenc
Publisher: John Wiley & Sons
Release Date: 2007-07-31
Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, vector control, satellite detection, surveillance, modeling, and high-throughput technologies. The final part explores specialized topics of current concern, including bioterrorism, world market and infectious diseases, and antibiotics for public health. Each article is written by one or more leading experts in the field of infectious diseases. These experts place all the latest findings from various disciplines in context, helping readers understand what is currently known, what the next generation of breakthroughs is likely to be, and where more research is needed. Several features facilitate research and deepen readers' understanding of infectious diseases: Illustrations help readers understand the pathogenesis and diagnosis of infectious diseases Lists of Web resources serve as a gateway to important research centers, government agencies, and other sources of information from around the world Information boxes highlight basic principles and specialized terminology International contributions offer perspectives on how infectious diseases are viewed by different cultures A special chapter discusses the representation of infectious diseases in art With its multidisciplinary approach, this encyclopedia helps point researchers in new promising directions and helps health professionals better understand the nature and treatment of infectious diseases.